Annona Muricata vs Berberis lycium

A tropical tree whose leaves contain acetogenins with specific toxicity to cancer cells; widely used across Latin America, Africa, and Southeast Asia for cancer support and parasites.

Northwest Himalayan barberry; bark paste (Rasaut) used in Unani medicine for eye conditions and infections.

Annonacin, Bullatacin, Squamocin, Flavonoids

berberine, berbamine, palmatine, oxyacanthine, tannins

Cancer treatment in tropical traditional medicine, Antimalarial and antiparasitic, Diabetes and blood sugar management

eye infections, conjunctivitis, diabetes, infections, diarrhea

Anti-tumor acetogenins (highly potent), Antiparasitic and antimicrobial, Blood sugar regulation

antimicrobial, anti-diabetic, anti-inflammatory, ophthalmic

1-3g dried leaf as tea or 500mg extract twice daily

500mg extract 2x/day; paste for eye wash

Potential neurotoxicity with prolonged use (annonacin), May cause atypical Parkinson symptoms with chronic use

pregnancy, neonates

Atypical Parkinsonism with chronic use (annonacin), GI disturbance, Potential neurotoxicity

GI upset, hypoglycemia