Calamus Root vs Guayusa

Side-by-side comparison of medicinal herbs

Herb

Calamus Root

Acorus calamus

Nootropic

Ilex guayusa

Nootropic

Calamus Root

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Guayusa

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Description

Ayurvedic and Native American wetland rhizome; nootropic and digestive; some chemotypes contain beta-asarone carcinogen.

An Amazonian holly tree related to yerba mate, traditionally used by Kichwa for lucid dreaming and sustained energy.

Active Compounds

beta-asarone, alpha-asarone, acorin, calamenol, shyobunone

Caffeine, L-theanine, Theobromine, Chlorogenic acids

Traditional Uses

Ayurvedic nootropic medhya herb, Native American stimulant chewing, Digestive conditions, Speech and learning

Energy and focus, Lucid dreaming, Hunting preparation, Digestive aid

Modern Uses

Cognitive enhancement, Digestive stimulant, Anticonvulsant research, Neurological support

Antioxidant, Cognitive enhancement, Sustained energy

Adult Dosage

1-3g diploid variety; avoid tetraploid

2-4g dried leaves as tea 1-3x daily

Contraindications

Pregnancy caution, Beta-asarone carcinogen in some varieties, Liver disease

Anxiety disorders, Insomnia, Heart arrhythmias

Side Effects

Beta-asarone carcinogenic in high-asarone varieties

Insomnia, Nervousness, GI upset

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E