Chelidonium Majus vs Macaranga Tanarius

A European herb with alkaloids (chelidonine, berberine) used for liver and gallbladder conditions, warts, and skin conditions; German Commission E approved for gallbladder conditions.

Fast-growing pioneer tree of Southeast Asian forests used in Philippine and Indonesian traditional medicine for wound healing, skin conditions, and liver support.

Chelidonine, Coptisine, Berberine, Sanguinarine

tanariflavanones, macarangaflavones, flavonoids, tannins

Liver and gallbladder disorders in European medicine, Wart removal (fresh latex), Eye inflammation in folk medicine

wound healing, skin conditions, liver disorders, inflammation, ulcers

Gallbladder and bile stimulation, Antispasmodic for bile ducts, Topical for warts

wound healing, anti-inflammatory, hepatoprotective, antimicrobial

2-4mg total alkaloids or 2-3ml tincture three times daily

Bark or leaf decoction 200ml 2x daily or topical leaf paste

Hepatotoxic in high doses – strict dosing required, Avoid in biliary obstruction, Avoid in pregnancy

pregnancy, allergy

Hepatotoxicity in excess, GI irritation, Contact dermatitis from latex

mild digestive upset