Frangula Purshiana vs Rheum Tanguticum

Deciduous tree of the Pacific Northwest used by Indigenous peoples and in botanical medicine as a laxative, one of the gentlest stimulant laxatives in traditional use.

Root of Tibetan rhubarb used in TCM and Tibetan medicine as a powerful purgative, liver herb, and blood-moving agent.

cascarosides A-D, aloe-emodin, chrysophanol, anthraquinones, tannins

emodin, rhein, aloe-emodin, chrysophanol, physcion

constipation, liver congestion, gallbladder disorders, digestive sluggishness

constipation, liver disease, blood stasis, fever, infections

stimulant laxative, cholagogue, digestive tonic

laxative, anti-inflammatory, antimicrobial, anticancer research

300–500mg aged bark extract or 1–2g aged bark tea at night

3–12g decoction or 200–500mg extract

pregnancy, nursing, abdominal pain, inflammatory bowel disease, children

pregnancy, nursing, inflammatory bowel disease, appendicitis symptoms

diarrhea, electrolyte imbalance, melanosis coli with long-term use

diarrhea, abdominal cramps, potassium loss, electrolyte imbalance