Guarana Seed vs Guayusa

Side-by-side comparison of medicinal herbs

Herb

Guarana Seed

Paullinia cupana

Nootropic

Ilex guayusa

Nootropic

Guarana Seed

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Guayusa

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Description

Amazonian stimulant seed with highest caffeine content of any plant; Guarani people use for energy, mental clarity, and as medicine.

An Amazonian holly tree related to yerba mate, traditionally used by Kichwa for lucid dreaming and sustained energy.

Active Compounds

caffeine, theobromine, theophylline, tannins, saponins

Caffeine, L-theanine, Theobromine, Chlorogenic acids

Traditional Uses

Guarani energy tonic, Diarrhea remedy, Mental clarity, Athletic performance

Energy and focus, Lucid dreaming, Hunting preparation, Digestive aid

Modern Uses

Stimulant, Weight management, Athletic performance, Cognitive enhancement

Antioxidant, Cognitive enhancement, Sustained energy

Adult Dosage

40-300mg caffeine equivalent daily

2-4g dried leaves as tea 1-3x daily

Contraindications

Anxiety disorders, Insomnia, Hypertension, Heart conditions, Pregnancy caution

Anxiety disorders, Insomnia, Heart arrhythmias

Side Effects

Insomnia, Tachycardia, Anxiety, GI upset

Insomnia, Nervousness, GI upset

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E