Harmel vs Diospyros virginiana

Widely used in Middle Eastern, North African, and Central Asian traditional medicine as a psychoactive, antimicrobial, and anthelmintic herb; seeds burned ritually.

A North American persimmon used by Native Americans for sore throat, fever, and as an astringent food plant.

harmine, harmaline, tetrahydroharmine, vasicine, rutin

tannins, ellagic acid, flavonoids, ascorbic acid

Spiritual purification, Anthelmintic use, Fever treatment, Rheumatic conditions

Sore throat gargle, Fever treatment, Nutritive food

MAO inhibitor activity, Antifungal effects, Antibacterial properties, Antiparasitic action

Antimicrobial activity, Antioxidant use, Astringent application

Seeds: 3-7g total (professional guidance only)

2-3g bark as tea; gargle with bark tea

MAOI interactions (dangerous), Pregnancy, Children, Many medications

Unripe fruit very astringent

MAOI interactions — potentially fatal, Hallucinations at high doses, Vomiting

Constipation from unripe fruit