PEA Source vs St. Johns Wort Oil

Side-by-side comparison of medicinal herbs

Herb

PEA Source

Palmitoylethanolamide natural

Analgesic

Hypericum perforatum oleum

Analgesic

PEA Source

✅ Generally safe in pregnancy

✅ Generally safe while nursing

St. Johns Wort Oil

❌ Not recommended in pregnancy

✅ Generally safe while nursing

Description

Endogenous fatty acid amide with analgesic and neuroprotective action.

Infused oil of St Johns Wort in olive oil; topical anti-inflammatory for nerve pain, bruises, and burns.

Active Compounds

Palmitoylethanolamide, Endocannabinoid-like compound

hypericin, pseudohypericin, hyperforin, flavonoids, tannins

Traditional Uses

Chronic pain, Neuropathy, Inflammation, Sciatic pain

Topical wound and nerve pain treatment, Burns and bruises, Medieval wound oil, Nerve pain conditions topically

Modern Uses

Endocannabinoid modulator, Mast cell stabilizer, Neuroprotective

Topical analgesic, Anti-inflammatory, Wound healing, Antiviral topical

Adult Dosage

300-600mg 2-3x daily

Topical as needed

Contraindications

None commonly known

Photosensitivity with topical use in sun, Not for internal use

Side Effects

Very rare GI upset

Photosensitivity with sun exposure after topical use

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E