Piule vs Psychotria nervosa

Side-by-side comparison of medicinal herbs

Herb

Piule

Ipomoea tricolor

Nervine

Nervine

Piule

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Psychotria nervosa

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Description

Sacred morning glory seeds used by Mazatec healers in Mexico for divination and healing ceremonies.

Florida native Rubiaceae; leaves used by Seminole in folk medicine; related to psychedelic Psychotria.

Active Compounds

ergine, ergometrine, isoergine, lysergic acid

purine alkaloids, flavonoids, tannins

Traditional Uses

ceremonial divination, headache, fever

fever, headache, fatigue, nervous conditions

Modern Uses

entheogenic, serotonergic

antipyretic, stimulant (mild), nervine

Adult Dosage

Traditional ceremonial use only

3-5g leaf tea 2x/day

Contraindications

pregnancy, cardiovascular conditions, self-administration

pregnancy

Side Effects

hallucinations, nausea, vasoconstriction

mild stimulant effects, GI upset

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E