Saffron vs Hops

Saffron is the most expensive spice in the world by weight, derived from the stigmas of the crocus flower. It has been used medicinally for over 3,600 years in Persian, Greek, and Ayurvedic traditions. Modern clinical trials have demonstrated significant antidepressant effects comparable to some pharmaceutical antidepressants.

Hops are the female flowers of the hop plant, best known for their use in brewing beer but also valued medicinally for their sedative and calming properties. They have been used in European herbal medicine since at least the 9th century. The sedative effects are attributed to the degradation products of alpha acids.

Crocin, Crocetin, Safranal, Picrocrocin, Kaempferol

2-Methyl-3-buten-2-ol, Xanthohumol, Humulone, Lupulone, 8-Prenylnaringenin

Depression treatment, Aphrodisiac, Digestive aid, Eye health, Menstrual support

Sleep aid, Anxiety relief, Digestive bitter, Appetite stimulant, Menstrual support

Depression (mild to moderate), PMS symptoms, Macular degeneration, Appetite control, Anxiety

Insomnia, Anxiety and restlessness, Menopausal symptoms, Digestive support, Tension headaches

15-30mg standardized saffron extract daily

300-500mg extract daily, or 1-2 cups tea before bedtime

Pregnancy (high doses can be abortifacient), Bipolar disorder, Bleeding disorders, Low blood pressure

Depression (may worsen), Hormone-sensitive conditions (estrogenic effects), Concurrent sedative medications

Nausea, Dizziness, Dry mouth, Headache, Anxiety (at very high doses), Toxicity above 5g

Drowsiness, Dizziness, GI upset, Allergic reactions, Depressive symptoms