Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Deoxypodophyllotoxin and other petroleum ether fraction isolates show antitumor and antiproliferative activity against breast cancer (MCF7, MDA-MB-231), hepatocellular carcinoma (HepG2), osteosarcoma (MG-63), melanoma (B16), and cervical carcinoma (HeLa) cells in vitro [PMID:23818925, PMID:24761904, PMID:26287153].
Root extracts attenuated mucus secretion, inflammatory cell infiltration, and Th2 cytokine levels in OVA-induced asthma mouse models [PMID:30552991]. A fermented extract mixture containing A. sylvestris decreased coughs in guinea pigs and reduced lung inflammation in mice [PMID:34393544].
Oral administration of deoxypodophyllotoxin (5 and 10 mg/kg) decreased lipid accumulation in the liver of high-fat diet-induced C57BL/6 mice [PMID:30148990].
Root polysaccharides (AP) demonstrated in vivo anti-aging activity in D-gal-induced aging mice by boosting antioxidant enzymes and mitigating immune decline [PMID:39233161].
Aqueous leaf extracts inhibited LPS-induced secretion of nitric oxide and prostaglandin E2 in RAW264.7 cells and attenuated inflammatory mediators (TNF-alpha, IL-1beta, IL-6) [PMID:29377739].
Synthèse des preuves
Sources PubMed
- 1.PMID: 38674496 (2024) — Anthriscus sylvestris-Noxious Weed or Sustainable Source of Bioactive Lignans? · Plants (Basel, Switzerland)
- 2.PMID: 37948767 (2023) — Anthriscus sylvestris Deoxypodophyllotoxin Synthase Involved in the Podophyllotoxin Biosynthesis. · Plant & cell physiology
- 3.PMID: 34560578 (2021) — Comprehensive study of Anthriscus sylvestris lignans. · Phytochemistry
- 4.PMID: 39233161 (2024) — Structural characterization, anti-aging activity and mechanisms investigation in vivo of a polysaccharide from Anthriscus sylvestris. · International journal of biological macromolecules
- 5.PMID: 36144804 (2022) — Quantitative HPLC-UV Study of Lignans in Anthriscus sylvestris.