Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Alcoholic stem bark extract (100-200 mg/kg) exhibited significant hepatoprotective activity in CCl4-intoxicated rats [PMID: 17827931]. Leaf extract mitigated acute liver failure and nephrotoxicity in thioacetamide-induced male rats [PMID: 32226246].
Treatment (200-400 mg/kg) in STZ-induced diabetic rats dramatically reduced blood glucose and HbA1c levels and increased SOD and catalase levels [PMID: 37969205].
Used as part of a standalone Ayurveda management regimen in a 34-year-old female case report [PMID: 37865054].
Seed lectin exhibited anti-proliferative activity on nasopharyngeal carcinoma HONE1 cells (IC50 12.8 μM) and slightly inhibited hepatoma growth [PMID: 25240852]. Root compounds (specifically dehydropipernonaline) showed significant bioactivity against prostate (DU-145, PC-3), colon (HT-29), and breast (MCF-7) cancer cell lines [PMID: 39779566].
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 37865054 (2023) — Standalone Ayurveda management of Hodgkin's lymphoma: A case report. · Journal of Ayurveda and integrative medicine
- 2.PMID: 39974713 (2024) — Influence of microwave processing on nutritional, anti-nutritional, antioxidant and sensory characteristics of kachnar powder and supplemented flatbreads. · Food chemistry: X
- 3.PMID: 17827931 (2007) — Hepatoprotective properties of Bauhinia variegata bark extract. · Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
- 4.PMID: 37929082 (2023) — Wild Edible Flowers of Western Himalayas: Nutritional Characterization, UHPLC-QTOF-IMS-Based Phytochemical Profiling, Antioxidant Properties, and In Vitro Bioaccessibility of Polyphenols. · ACS omega
- 5.PMID: 35438173 (2022) — Chromosomal-level genome assembly of the orchid tree Bauhinia variegata (Leguminosae; Cercidoideae) supports the allotetraploid origin hypothesis of Bauhinia.