Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
PubMed · <i>Monarda didyma</i> Hydrolate Affects the Survival and the Behaviour of <i>Drosophila suzukii</i>. (2022)
PubMed · Unveiling the geroprotective potential of Monarda didyma L.: insights from in vitro studies and a randomized clinical trial on slowing biological aging and improving quality of life. (2025)
Révisé par : HerbAlly Editorial Team, Medical herbalists and healthcare professionals
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Monarda didyma is an aromatic herb of the Lamiaceae family with demonstrated antioxidant, anti-inflammatory, and antimicrobial properties [PMID:36438580, 34199656]. Recent clinical evidence suggests potential geroprotective effects on biological aging [PMID:40064804].
Contexte
Monarda didyma, also known as scarlet beebalm, is a herbaceous perennial native to eastern North America and cultivated in regions such as Italy and Korea [PMID:38202420, 30732007, 12532728]. It is characterized by square stems, opposite leaves, and bright scarlet-red flowers [PMID:38202420, 12532728].
Usages traditionnels
It has been used as a domestic medicine, specifically for treating digestive disorders, and the leaves and flowering stems are used as a carminative, diuretic, expectorant, febrifuge, rubefacient, stimulant, and antihelmintic [PMID:12532728].
Composés actifs
The essential oil is rich in phenolic terpenoids, primarily carvacrol, thymol, and p-cymene [PMID:36438580, 28157176, 39812868]. Other identified compounds include terpinolene, delta-3-carene, myrcene, and camphene [PMID:28157176]. Extracts also contain polyphenols and flavonoids, including rutin, hyperoside, quercitrin, luteolin, and quercetin [PMID:38202420, 12532728].
Mécanisme d'action
Anti-inflammatory effects are associated with the decreased expression of pro-inflammatory cytokine IL-6 and increased expression of miR-146a, suggesting involvement of the Toll-like receptor-4 signaling pathway [PMID:36438580]. Antibacterial activity against Carbapenem-resistant Klebsiella pneumoniae involves cell membrane damage and interference with respiratory metabolism in the tricarboxylic acid (TCA) and pentose phosphate (PPP) pathways [PMID:37730531]. In fungi, the component thymol may bind to FKS1 to disrupt the cell wall [PMID:39078084].
Preuves cliniques
Preuve BBiological Aging
Daily oral supplementation with M. didyma extract significantly improved leukocyte telomere length (LTL) and stabilized DNA methylation age (DNAmAge) [PMID:40064804]
Synthèse des preuves
Evidence consists primarily of in vitro studies and animal models demonstrating antimicrobial and antioxidant activity, with one randomized clinical trial suggesting geroprotective benefits.
Sources PubMed
1.PMID: 35323578 (2022) — Monarda didyma Hydrolate Affects the Survival and the Behaviour of Drosophila suzukii. · Insects
2.PMID: 36924719 (2023) — Nano-emulsification essential oil of Monarda didyma L. to improve its preservation effect on postharvest blueberry. · Food chemistry
3.PMID: 40064804 (2025) — Unveiling the geroprotective potential of Monarda didyma L.: insights from in vitro studies and a randomized clinical trial on slowing biological aging and improving quality of life. · GeroScience
4.PMID: 36438580 (2022) — Chemical composition, antioxidant and anti-inflammatory properties of Monarda didyma L. essential oil. · PeerJ
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
— The Essential Oil of Monarda didyma L. (Lamiaceae) Exerts Phytotoxic Activity in Vitro against Various Weed Seed.
· Molecules (Basel, Switzerland)
6.PMID: 34199656 (2021) — The Biological Activity of Monarda didyma L. Essential Oil and Its Effect as a Diet Supplement in Mice and Broiler Chicken. · Molecules (Basel, Switzerland)
7.PMID: 38202420 (2023) — Pharmacognostic Evaluation of Monarda didyma L. Growing in Trentino (Northern Italy) for Cosmeceutical Applications. · Plants (Basel, Switzerland)
8.PMID: 37730531 (2023) — In-vitro antibacterial activity and mechanism of Monarda didyma essential oils against Carbapenem-resistant Klebsiella pneumoniae. · BMC microbiology
9.PMID: 12532728 (2002) — [Analysis of flavonoids in the flowers and leaves of Monarda didyma L]. · Medicina (Kaunas, Lithuania)
10.PMID: 36986824 (2023) — Comparative HPLC-DAD-ESI-QTOF/MS/MS Analysis of Bioactive Phenolic Compounds Content in the Methanolic Extracts from Flowering Herbs of Monarda Species and Their Free Radical Scavenging and Antimicrobial Activities. · Pharmaceutics
11.PMID: 33477717 (2021) — Is the Antimicrobial Activity of Hydrolates Lower than That of Essential Oils? · Antibiotics (Basel, Switzerland)
12.PMID: 34371571 (2021) — Chemical Composition and Nematicidal Properties of Sixteen Essential Oils-A Review. · Plants (Basel, Switzerland)
13.PMID: 39812868 (2025) — Essential oil and phenolic compounds in different organs and developmental stages of Monarda didyma L., and their biological activity. · Planta
14.PMID: 30732007 (2011) — First Report of Powdery Mildew Caused by Golovinomyces biocellatus on Monarda didyma in Korea. · Plant disease
15.PMID: 32481758 (2020) — Bioactive Compounds and Aroma Profile of Some Lamiaceae Edible Flowers. · Plants (Basel, Switzerland)
16.PMID: 30155907 (2018) — Disease where you dine: plant species and floral traits associated with pathogen transmission in bumble bees. · Ecology
17.PMID: 39063571 (2024) — The Impact of Plant Essential Oils on the Growth of the Pathogens Botrytis cinerea, Fusarium solani, and Phytophthora pseudocryptogea. · Life (Basel, Switzerland)
18.PMID: 35320907 (2022) — Effect of salicylic acid on phenolic compounds, antioxidant and antihyperglycemic activity of Lamiaceae plants grown in a temperate climate. · Frontiers in bioscience (Elite edition)
19.PMID: 30754519 (2010) — Evaluation of Microbial, Botanical, and Organic Treatments for Control of Peanut Seedling Diseases. · Plant disease
20.PMID: 39078084 (2024) — A Novel Preservative Film with a Pleated Surface Structure and Dual Bioactivity Properties for Application in Strawberry Preservation due to Its Efficient Apoptosis of Pathogenic Fungal Cells. · Journal of agricultural and food chemistry
21.PMID: 34759738 (2021) — Chromatographic profiles and antimicrobial activity of the essential oils obtained from some species and cultivars of the Mentheae tribe (Lamiaceae). · Saudi journal of biological sciences
22.PMID: 33957454 (2021) — Acidic pH-responsive changes of DNA structure and surface dynamics as probed with ultrasensitive Raman spectroscopy. · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy