Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Borneol exhibits neuroprotective effects and can be used in delivery systems to restore intracellular Ca2+ and redox homeostasis while inhibiting apoptosis pathways [PMID:39804950, PMID:34017247]
Borneol is applied in the protection and treatment of CVDs due to anti-inflammatory, anti-oxidant, and anti-coagulant activities [PMID:36087846, PMID:33892091]
Natural borneol combined with sodium valproate (VPA) showed augmented efficacy in vivo by inhibiting TAGLN/HDAC2 function [PMID:38087889]
L-borneol promotes the differentiation of hair follicle stem cells into basal layer cells to repair skin wounds [PMID:40378434]; alum-borneol combinations are used in clinical burn treatment [PMID:35731421]
Borneol enantiomers can inhibit P-glycoprotein (Pgp), thereby increasing the accumulation of drugs like mitoxantrone in cells [PMID:33378196]
Interactions médicamenteuses
Synthèse des preuves
Sources PubMed
- 1.PMID: 38087889 (2024) — Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation. · Advanced science (Weinheim, Baden-Wurttemberg, Germany)
- 2.PMID: 37321057 (2023) — Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 3.PMID: 39804950 (2025) — Traditional Chinese Medicine Borneol-Based Polymeric Micelles Intracerebral Drug Delivery System for Precisely Pathogenesis-Adaptive Treatment of Ischemic Stroke. · Advanced science (Weinheim, Baden-Wurttemberg, Germany)
- 4.PMID: 34104738 (2021) — The complete chloroplast genome sequence of Dryobalanops aromatica. · Mitochondrial DNA. Part B, Resources
- 5.PMID: 36793954