Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Oral administration of PM-EVLPs substantially mitigated experimental colitis in mice by targeting inflamed colon macrophages [PMID:40685348].
Wu-Mei-Pill (WMP) and Wu Mei Wan (WMW) demonstrated therapeutic impacts on tumor number, tumor load, and cancer stemness in mouse models [PMID:38452403, PMID:39489363].
A 70% ethanol extract of P. mume bark induced vasorelaxant effects in rat thoracic aortic rings and hypotensive effects in spontaneous hypertensive rats [PMID:36671646]. Infused juice concentrate (bainiku-ekisu) attenuated inflammatory vascular remodeling in Angiotensin II-induced hypertensive mice [PMID:37308550].
Purified polyphenols (L1) showed anticancer activity against HeLa, HepG2, MCF-7, and A549 cell lines [PMID:37092717].
In a human study of participants over 60, serum osteocalcin (OCN) levels were significantly higher in the high ume intake group compared to the low intake group [PMID:35150233].
Interactions médicamenteuses
Synthèse des preuves
Sources PubMed
- 1.PMID: 40685348 (2025) — Prunus mume derived extracellular vesicle-like particles alleviate experimental colitis via disrupting NEK7-NLRP3 interaction and inflammasome activation. · Journal of nanobiotechnology
- 2.PMID: 38452403 (2024) — Mechanic evaluation of Wu-Mei-Pill on colitis-associated colorectal cancer: An integrated transcriptomics, metabolomics, and experimental validation study. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 3.PMID: 31491438 (2020) — Anticancer properties of Prunus mume extracts (Chinese plum, Japanese apricot). · Journal of ethnopharmacology
- 4.PMID: 23271652 (2012) — The genome of Prunus mume. · Nature communications
- 5.PMID: 33310179 (2021)