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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Rhamnus cathartica
Arbuste laxatif européen dont les baies étaient utilisées en médecine médiévale comme purgatif puissant.
Buckthorn (Rhamnus cathartica) is a European shrub whose dried bark has been used historically as a strong purgative, primarily for constipation and bowel cleansing. Its laxative effects are attributed to anthraquinone compounds such as emodin, chrysophanol, and rhein, which stimulate colonic motility. Modern evidence supports short-term use but warns against prolonged administration due to risks of electrolyte imbalance and dependence.
The anthraquinone glycosides (e.g., emodin, rhein) in buckthorn bark are hydrolyzed by colonic bacteria to active aglycones, which inhibit Na+/K+-ATPase in enterocytes, reducing water and electrolyte absorption. They also stimulate peristalsis by activating prostaglandin E2 (PGE2) and nitric oxide (NO) pathways, and may interact with serotonin (5-HT4) receptors in the gut. Chronic use leads to melanosis coli and loss of colonic tone.
Arbuste laxatif européen dont les baies étaient utilisées en médecine médiévale comme purgatif puissant.
Buckthorn (Rhamnus cathartica) is a European shrub whose dried bark has been used historically as a strong purgative, primarily for constipation and bowel cleansing. Its laxative effects are attributed to anthraquinone compounds such as emodin, chrysophanol, and rhein, which stimulate colonic motility. Modern evidence supports short-term use but warns against prolonged administration due to risks of electrolyte imbalance and dependence.
The anthraquinone glycosides (e.g., emodin, rhein) in buckthorn bark are hydrolyzed by colonic bacteria to active aglycones, which inhibit Na+/K+-ATPase in enterocytes, reducing water and electrolyte absorption. They also stimulate peristalsis by activating prostaglandin E2 (PGE2) and nitric oxide (NO) pathways, and may interact with serotonin (5-HT4) receptors in the gut. Chronic use leads to melanosis coli and loss of colonic tone.