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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Sanguisorba minor (Burnet Salad) is a perennial medicinal vegetable native to the Northern Hemisphere, particularly the Mediterranean region, known for its antioxidant and antimicrobial properties [PMID: 30761392, 34616302, 38140461].
Contexte
Sanguisorba minor Scop. is a member of the Rosaceae family characterized by elongated, imparipinnate leaves and densely clustered flower heads [PMID: 37299107]. It is distributed across temperate, arctic, or alpine areas of the Northern Hemisphere [PMID: 37299107].
Usages traditionnels
It is used as an edible wild plant in the Mediterranean diet, where young shoots and leaves are consumed in salads [PMID: 34616302]. It has been traditionally used to cure various ailments [PMID: 36748966] and is used in seasoning desserts, juices, and beverages [PMID: 38140461]. In Pinarbasi, Turkey, it is used in folk medicine for treating peptic ulcer symptoms such as stomach ache and heartburn [PMID: 16085377].
Composés actifs
The plant contains phenolic compounds, including flavonoids (such as rutin, apigenin, quercetin, myricetin, and kaempferol), tannins (predominantly hydrolysable ellagitannins like Sanguiin H-10 and lambertianin C), and phenolic acids (gallic acid, ellagic acid) [PMID: 38140461, 32470801, 34982352, 12770593, 38822060]. Quercetin-3-glucuronide has been identified as a key constituent for plasmin inhibition [PMID: 22348918].
Mécanisme d'action
S. minor exhibits antioxidant capacity and may attenuate injury via the Nrf2/HO-1 pathway [PMID: 38140461, 36748966]. It also modulates enzymatic activities, specifically inhibiting human plasmin [PMID: 22348918].
Preuves cliniques
Preuve DGastric Ulcers
Oral decoctions of aerial parts showed significant gastric protection and healing effects in ethanol-induced rat models [PMID: 16085377]
Preuve DMyocardial Infarction
Hydro-ethanolic extract of aerial parts (100 or 300 mg/kg) demonstrated cardioprotective effects against isoprenaline-induced MI in rats [PMID: 38223198]
Preuve DMemory Loss
Hydro-ethanolic extract (50-200 mg/kg) reduced escape latency and travelled distance in scopolamine-induced memory loss rat models [PMID: 34982352]
Preuve DAging (Brain and Liver Injury)
Standardized extract attenuated oxidative injury and pathology in aging rats [PMID: 36748966]
Preuve DViral Infections
Aqueous extracts of S. minor magnolii exhibited in vitro anti-HIV-1 activity [PMID: 11483387] and antiviral activity against HSV-1 and VSV [PMID: 11113996]
Preuve DCancer Cell Migration
Sécurité et effets indésirables
In vivo toxicity assessments in mice showed a no-observed-adverse-effect level (NOAEL) up to 2,000 mg/kg and an LD50 over 3,000 mg/kg for the hydroalcoholic extract; no marked changes in body weight or neuromuscular coordination were observed [PMID: 34881541].
Synthèse des preuves
The current evidence is primarily based on in vitro studies and animal models (Level D), demonstrating significant antioxidant, neuroprotective, cardioprotective, and antimicrobial potential. No human clinical trials were provided.
Sources PubMed
1.PMID: 37299107 (2023) — Sanguisorba minor Scop.: An Overview of Its Phytochemistry and Biological Effects. · Plants (Basel, Switzerland)
2.PMID: 34616302 (2021) — A Comprehensive Review of Genus Sanguisorba: Traditional Uses, Chemical Constituents and Medical Applications. · Frontiers in pharmacology
3.PMID: 36559673 (2022) — Evaluation of Polyphenolic Composition and Antimicrobial Properties of Sanguisorba officinalis L. and Sanguisorba minor Scop. · Plants (Basel, Switzerland)
4.PMID: 38140461 (2023) — Assessment of Chemical Composition and In Vitro Antioxidant, Antidiabetic, Anticholinesterase and Microbial Virulence-Quenching Effects of Salad Burnet (Sanguisorba minor L.) Harvested from Algeria. · Plants (Basel, Switzerland)
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
Ethanol extract suppresses plasmin-mediated mechanisms of cancer cell migration in vitro [PMID: 22348918]
Preuve DBacterial Infections
Demonstrated antimicrobial activity, specifically against Salmonella typhimurium [PMID: 32470801]
(2023)
— Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats.
· Frontiers in pharmacology
6.PMID: 34982352 (2022) — Effect of Sanguisorba minor on scopolamine-induced memory loss in rat: involvement of oxidative stress and acetylcholinesterase. · Metabolic brain disease
7.PMID: 11483387 (2001) — Anti-HIV activity of medicinal plant extracts. · Journal of ethnopharmacology
8.PMID: 34881541 (2022) — Acute and sub-acute toxicity assessment of the standardized extract of Sanguisorba minor in vivo. · Journal of complementary & integrative medicine
9.PMID: 32470801 (2020) — Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes. · Food chemistry
10.PMID: 36748966 (2022) — Standardized extract of Sanguisorba minor attenuates injury in aging rat model via the Nrf2/HO‑1 pathway. · Acta neurobiologiae experimentalis
12.PMID: 38822060 (2024) — Investigating the efficacy of purified tannin extracts from underutilized temperate forages in reducing enteric methane emissions in vitro. · Scientific reports
13.PMID: 22348918 (2012) — Sanguisorba minor extract suppresses plasmin-mediated mechanisms of cancer cell migration. · Biochimica et biophysica acta
14.PMID: 11113996 (2000) — Search for antiviral activity in higher plant extracts. · Phytotherapy research : PTR
15.PMID: 30761392 (2019) — Chemical composition and bioactive properties of Sanguisorba minor Scop. under Mediterranean growing conditions. · Food & function
16.PMID: 16085377 (2005) — Anti-ulcerogenic activity of some plants used in folk medicine of Pinarbasi (Kayseri, Turkey). · Journal of ethnopharmacology