Camphor Basil (Ocimum kilimandscharicum): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does camphor basil work for respiratory conditions?

Camphor basil contains camphor and 1,8-cineole as primary active compounds. These volatile oils act as bronchodilators and expectorants, helping to clear mucus from airways. Camphor stimulates cold receptors in the respiratory tract, producing a cooling sensation that can ease breathing discomfort. The herb also demonstrates antimicrobial activity against certain respiratory pathogens. Evidence level: C (preliminary research and traditional use).

Does camphor basil interact with any medications?

Limited formal drug interaction studies exist for camphor basil. However, its camphor content may theoretically interact with medications metabolised by liver enzymes. Caution is advised when combining with anticoagulants, sedatives, or other camphor-containing products. The herb may enhance the effects of CNS depressants. Patients taking prescription medications should consult a healthcare provider before use. Evidence level: C (theoretical based on constituent properties).

What is the recommended dosage for camphor basil?

For adults, the traditional dosage is 2-3 grams of dried herb prepared as tea, consumed up to three times daily. For respiratory inhalation, use diluted essential oil only—never ingest the essential oil. Children should not use camphor basil due to camphor sensitivity risks. Always start with lower doses to assess individual tolerance. Evidence level: C (traditional use with limited clinical validation).

Is camphor basil safe during pregnancy?

Camphor basil is contraindicated during pregnancy and breastfeeding. The camphor content can cross the placenta and may stimulate uterine contractions or cause fetal toxicity. Pregnant women should avoid both internal use and topical application of camphor basil preparations. Women planning pregnancy should also avoid this herb. Evidence level: C (based on constituent safety profiles).

What is camphor basil used for in traditional medicine?

Camphor basil has been used extensively in East African traditional medicine, particularly by Maasai and other indigenous peoples. Traditional applications include treating malaria and fevers, respiratory infections, and various skin conditions including wounds. The herb is valued for its antimicrobial and anti-inflammatory properties. Modern research is investigating its antimalarial potential, though clinical evidence remains preliminary. Evidence level: C (traditional use supported by preliminary research).

What are the side effects of camphor basil?

Excessive intake can cause camphor toxicity, with symptoms including nausea, vomiting, confusion, and seizures. Undiluted essential oil may cause skin irritation, redness, or contact dermatitis. People with epilepsy should avoid camphor basil due to its potential to lower seizure threshold. Children are particularly susceptible to camphor toxicity and should not use this herb. Evidence level: C (based on constituent toxicity data).

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Ocimum kilimandscharicum, known as Camphor Basil, is a medicinal plant of the Lamiaceae family characterized by high concentrations of terpenoids, particularly camphor [PMID:34269773, PMID:29476116].

Contexte

Camphor Basil is an East African permanent evergreen plant [PMID:38144100]. It is phylogenetically close to O. tenuiflorum and other Ocimum species [PMID:34269773].

Usages traditionnels

In Kenya, it has been used to treat measles, stomachaches, diarrhea, mosquito bites, congested chest, cough, and colds [PMID:38144100]. It is also popularly used against articular pain [PMID:33316364] and is traditionally used as a digestive and anti-diarrhoeal [PMID:23603195]. In Tanzania, fresh or smoked leaves are used as night-time insect repellents [PMID:18687119].

Composés actifs

Major components include camphor (ranging from 16.91% to 55% depending on tissue and chemotype), eugenol, 1,8-cineole, limonene, and $\beta$-caryophyllene [PMID:32619737, PMID:39584457, PMID:32613512, PMID:25172793]. Other identified compounds include thujopsene, flavonoid glycosides (kaempferol-3-rhamnoside, quercetin-3-O-rutinoside), and betulinic acid produced in callus cultures [PMID:38575203, PMID:39584457, PMID:25308098]. The leaves are also a source of potassium, magnesium, and calcium oxides [PMID:39584457].

Mécanisme d'action

The plant's essential oil and isolated camphor demonstrate anti-hyperalgesic and anti-inflammatory properties, including the inhibition of leukocyte rolling and adhesion to mesenteric microcirculation [PMID:33316364]. Leaf extracts have shown neuroprotective potential by ameliorating ischemia-reperfusion induced deficits in mice [PMID:27914825].

Preuves cliniques

Preuve DArticular pain/inflammation

Essential oil (EOOK) and camphor showed anti-inflammatory and analgesic effects in carrageenan-induced paw edema and zymosan-induced articular inflammation models [PMID:33316364].

Preuve DDiarrhea

Aqueous leaf extract significantly delayed the onset of defecation and reduced fecal weight in castor-oil induced diarrhea models in rats and mice [PMID:23603195].

Preuve DIschemia-reperfusion brain injury

Leaf extract (OKLE) ameliorated functional and biochemical deficits and improved memory in mice [PMID:27914825].

Preuve DPolycystic Ovary Syndrome (PCOS)

Total extract and ethyl acetate fraction improved insulin sensitivity and restored normal ovarian functions in letrozole-induced PCOS rat models [PMID:31295470].

Preuve DBacterial infections

Ethanol leaf extracts showed antimicrobial activity against Bacillus subtilis, E. coli, and Staphylococcus aureus [PMID:39584457].

Synthèse des preuves

The current evidence is based primarily on in vitro studies and animal models (Level D), demonstrating significant pharmacological potential for anti-inflammatory, anti-diarrheal, and neuroprotective effects, as well as insecticidal activity.

Sources PubMed

1.PMID: 34269773 (2021) — The complete chloroplast genome and phylogenetic analysis of Ocimum kilimandscharicum Gurke (Camphor Basil) from India. · Mitochondrial DNA. Part B, Resources
2.PMID: 32619737 (2020) — Biosynthesis and tissue-specific partitioning of camphor and eugenol in Ocimum kilimandscharicum. · Phytochemistry
3.PMID: 38575203 (2024) — Ocimum kilimandscharicum 4CL11 negatively regulates adventitious root development via accumulation of flavonoid glycosides. · The Plant journal : for cell and molecular biology
4.PMID: 38144100 (2023) — Phytochemical Screening and GC-MS Analysis of Methanolic and Aqueous Extracts of Ocimum kilimandscharicum Leaves. · ACS omega
5.PMID: 33316364 (2021) — Analgesic and anti-inflammatory articular effects of essential oil and camphor isolated from Ocimum kilimandscharicum Gürke leaves.

Camphor Basil

Sources et citations

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