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Carum Carvi Herb
Carum carvi
remède contre les coliques dans la médecine populaire européenne
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 28 articles PubMed · modèle : gemma4:31b
Résumé
Carum carvi (caraway) is a medicinal plant used traditionally for gastrointestinal issues and as a galactagogue [PMID:30000850, PMID:30374904].
Contexte
Carum carvi, commonly known as caraway, is a member of the Apiaceae family grown worldwide and used as a cooking spice and in folk medicine [PMID:24459470, PMID:37474939].
Usages traditionnels
Traditional uses include the treatment of indigestion, pneumonia, and serving as an appetizer, galactagogue, and carminative [PMID:30374904]. In Persian traditional medicine, it has been used to decrease breastmilk oversupply [PMID:30000850].
Composés actifs
The seeds contain volatile oils, most prominently carvone and limonene [PMID:30000850]. Other constituents include carveol [PMID:35121309], flavonoids (such as quercetin 3-glucuronide, isoquercitrin, and kaempferol 3-glucoside) [PMID:910554], monoterpenoid glucosides, and alkaloids [PMID:34834797].
Mécanisme d'action
Caraway oil is noted for spasmolytic and analgesic effects in gastroenterological medicine [PMID:32711288]. In animal models of colitis, a combination of caraway and peppermint oil (Menthacarin) shifted the colonic cytokine profile toward a regulatory/anti-inflammatory phenotype [PMID:32711288].
Preuves cliniques
Preuve BObesity
Caraway was a main ingredient of traditional anti-obesity drugs, which has been confirmed in two modern human clinical trials [PMID:30374904].
Preuve BLactation (Galactagogue effect)
No scientifically valid clinical trials support its use as a galactagogue, and one small, old study found no effect [PMID:30000850].
Sécurité et effets indésirables
The U.S. FDA recognizes caraway as 'generally recognized as safe' [PMID:30000850]. Common side effects are gastrointestinal, including heartburn, eructation, flatulence, and nausea [PMID:30000850]. Case reports indicate that caraway ingestion may increase TSH levels in patients with hypothyroidism [PMID:25616491].
Grossesse et allaitement
Maternal use has been advocated to reduce colic in breastfed infants, though no valid clinical trials support this [PMID:30000850]. Experimental administration of d-carvone to nursing mothers resulted in measurable amounts of the chemical in breast milk, with no adverse effects noted in mothers or infants [PMID:30000850].
Interactions médicamenteuses
Caraway ingestion has been associated with elevated TSH levels in patients taking levothyroxine [PMID:25616491].
Synthèse des preuves
Evidence is primarily based on traditional use, animal models (colitis, oral mucositis), and a few human case reports or clinical trials. Human clinical data for specific therapeutic claims is limited.
Sources PubMed
1.PMID: 30000850 (2006) — Peppermint oil. · American family physician
2.PMID: 30374904 (2019) — Caraway as Important Medicinal Plants in Management of Diseases. · Natural products and bioprospecting
3.PMID: 35549975 (2023) — Phytochemical constitutes and biological activities of essential oil extracted from irradiated caraway seeds (Carum carvi L.). · International journal of radiation biology
4.PMID: 24459470 (2013) — Effects of Carum carvi L. (Caraway) extract and essential oil on TNBS-induced colitis in rats. · Research in pharmaceutical sciences
5.PMID: 39086459 (2024) — Safety and efficacy of a feed additive consisting of an essential oil obtained from the fruit of Carum carvi L. (caraway oil) for all animal species (FEFANA asbl).
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 35121309 (2022) — Selective extraction of oxygenated terpene in caraway (Carum carvi L.) using subcritical water extraction (SWE) technique. · Food chemistry
7.PMID: 37474939 (2023) — The structural characterization and bioactivity assessment of nonspecific lipid transfer protein 1 (nsLTP1) from caraway (Carum carvi) seeds. · BMC complementary medicine and therapies
8.PMID: 35841634 (2022) — Caraway (Carum carvi L.) in fast-growing and slow-growing broiler chickens' diets and its effect on performance, digestive tract morphology and blood biochemical profile. · Poultry science
9.PMID: 22096320 (2011) — Cuminum cyminum and Carum carvi: An update. · Pharmacognosy reviews
10.PMID: 34270006 (2021) — Caraway (Carum carvi L.): Anther Culture and Production of DH Plants Caraway. · Methods in molecular biology (Clifton, N.J.)
11.PMID: 37004150 (2023) — More complex than you think: Taxonomic and temporal patterns of plant-pollinator networks of caraway (Carum carvi L.). · Molecular ecology
12.PMID: 33256083 (2020) — Repellent Effect of the Caraway Carum carvi L. on the Rice Weevil Sitophilus oryzae L. (Coleoptera, Dryophthoridae). · Insects
13.PMID: 32711288 (2020) — Menthacarin attenuates experimental colitis. · Phytomedicine : international journal of phytotherapy and phytopharmacology
14.PMID: 38729502 (2024) — Chitosan nanoemulsion incorporated with Carum carvi essential oil as ecofriendly alternative for mitigation of aflatoxin B1 contamination in stored herbal raw materials. · International journal of biological macromolecules
15.PMID: 16538005 (2006) — Inhibitory effects of caraway (Carum carvi L. ) and its component on N-methyl-N'-nitro-N-nitrosoguanidine-induced mutagenicity. · The journal of medical investigation : JMI
16.PMID: 30732417 (1997) — Transgenic caraway, Carum carvi L.: a model species for metabolic engineering. · Plant cell reports
17.PMID: 22117784 (2011) — Herbs in dentistry. · International dental journal
18.PMID: 26407909 (2016) — Hydroalcoholic extract of Carum carvi L. in oral mucositis: a clinical trial in male golden hamsters. · Oral diseases
19.PMID: 29134293 (2017) — Medicinal Foods for Functional GI Disorders. · Current gastroenterology reports
20.PMID: 22030309 (2012) — Food components with anticaries activity. · Current opinion in biotechnology
21.PMID: 34834797 (2021) — Effect of Elevated CO2 on Biomolecules' Accumulation in Caraway (Carum carvi L.) Plants at Different Developmental Stages. · Plants (Basel, Switzerland)
22.PMID: 17083431 (2006) — Effects of essential oils from fennel (Foeniculi aetheroleum) and caraway (Carvi aetheroleum) in pigs. · Journal of animal physiology and animal nutrition
23.PMID: 32525777 (2021) — Persian Herbal Medicine in Functional Dyspepsia: A Systematic Review. · Current drug discovery technologies
24.PMID: 36661234 (2023) — Effects of methyl jasmonate elicitation on the carvone and limonene contents, phenolic compounds and antioxidant activity in caraway (Carum carvi L.) callus cultures. · Natural product research
25.PMID: 25616491 (2015) — Carum induced hypothyroidism: an interesting observation and an experiment. · Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences
26.PMID: 910554 (1977) — [Isolation and identification of flavon(ol)-O-glycosides in caraway (Carum carvi L.), fennel (Foeniculum vulgare Mill.), anise (Pimpinella anisum L.), and coriander (Coriandrum sativum L.), and of flavon-C-glycosides in anise. I. Phenolics of spices (author's transl)]. · Zeitschrift fur Lebensmittel-Untersuchung und -Forschung