Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 26 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Aqueous extracts of cerasee fruit reduced hyperglycemia by 50% after 5 hours in streptozotocin-induced diabetic mice and improved glucose tolerance in normal mice [PMID:3899464].
Wild Bitter Melon (400 mg/kg daily) was investigated for its therapeutic potential to ameliorate immobility-induced muscle atrophy in a murine model [PMID:39086863].
Total phenolic extract of WBM leaf attenuated P. acnes-induced ear swelling and microabscesses in mice and suppressed pro-inflammatory cytokines (IL-8, IL-1β, TNF-α) in vitro [PMID:26098998, PMID:26624580].
Charantadiol A from WBM leaf significantly suppressed P. gingivalis-stimulated IL-6 and TNF-α in a periodontitis mouse model [PMID:34577123].
Ethanol extract of wild bitter melon demonstrated antibacterial and anti-biofilm activities against Streptococcus mutans and Lactobacillus acidophilus in vitro [PMID:41690644].
Synthèse des preuves
Sources PubMed
- 1.PMID: 36634725 (2023) — Effects of dietary wild bitter melon (Momordica charantia var. abbreviate Ser.) extract on glucose and lipid metabolism in HFD/STZ-induced type 2 diabetic rats. · Journal of ethnopharmacology
- 2.PMID: 31151277 (2019) — Investigation of Biological Activities of Wild Bitter Melon (Momordica charantia Linn. Var. Abbreviata Ser.). · Biomolecules
- 3.PMID: 39086863 (2024) — The therapeutic potential of Wild Bitter Melon to ameliorate muscle atrophy in a murine model. · Avicenna journal of phytomedicine
- 4.PMID: 41690644 (2026) — Anticariogenic potential, phytochemical and molecular docking analysis of Momordica charantia: An in vitro study. · Microbial pathogenesis
- 5.PMID: 26624580 (2015)