Citrus medica

Citrus medica peel contains active compounds, including flavonoids like hesperidin and volatile essential oils, which function as carminatives. These constituents are believed to relax gastrointestinal smooth muscle to relieve spasms and bloating while stimulating gastric secretions to improve digestion. Evidence Level: C.

Unlike grapefruit, Citrus medica is not widely associated with strong cytochrome P450 inhibition, suggesting a lower risk of major drug interactions. However, patients with citrus allergies should strictly avoid it. Due to limited specific clinical data, individuals taking prescription medications should consult a healthcare provider before use. Evidence Level: C.

Traditional usage suggests a dosage of 5 to 10 grams of dried Citrus medica peel prepared as a tea, taken twice daily. In some cultures, preserved peel is consumed as a digestive tonic. Because evidence is rated Level C, these recommendations are based on historical use rather than standardized clinical trials.

Citrus medica is generally considered safe during pregnancy when consumed in food amounts or traditional medicinal doses. The fruit provides vitamin C and has a history of use without reported teratogenic effects. However, pregnant women should avoid excessive consumption to prevent gastrointestinal upset from high acidity. Evidence Level: C/Traditional.

Citrus medica is primarily used as a digestive tonic to relieve nausea, indigestion, and respiratory complaints. The peel is valued in Ayurveda for settling the stomach and reducing fever. While these uses are supported by a long history of traditional application, clinical evidence is currently rated Level C.