Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
How does Commelina communis work to clear heat and fight infections?
Commelina communis contains bioactive compounds including commelinin, flavonoids, phenolics, and polysaccharides that contribute to its therapeutic effects. These compounds exhibit antiviral and anti-inflammatory properties through antioxidant activity and modulation of inflammatory pathways. In Traditional Chinese Medicine, the herb works by 'clearing heat' and 'detoxifying,' which corresponds to reducing inflammation and fighting infections. Evidence level C indicates limited clinical data, with most support coming from traditional use and preliminary pharmacological research.
Does Commelina communis interact with any medications?
There are no well-documented drug interactions for Commelina communis in current medical literature. However, due to limited clinical research (Evidence level C), potential interactions cannot be ruled out. The herb's flavonoid content could theoretically affect drug-metabolizing enzymes. Patients taking anticoagulants, immunosuppressants, or medications metabolized by the liver should exercise caution and consult a healthcare provider before use. Always disclose all herbal supplements to your physician to ensure safe coordinated care.
What is the recommended dosage of Commelina communis for adults?
The traditional adult dosage for Commelina communis is 5-10 grams of fresh herb or 3-6 grams of dried herb, prepared as a decoction. This dosing comes from Traditional Chinese Medicine practice (Evidence level C). Dosage may vary based on the specific condition being treated, individual constitution, and formulation. Always follow the guidance of a qualified herbalist or healthcare provider. Do not exceed recommended amounts without professional supervision.
Is Commelina communis safe to take during pregnancy?
Commelina communis is considered unsafe during pregnancy and should be avoided. In Traditional Chinese Medicine, this herb 'clears heat' and promotes detoxification, properties that may stimulate uterine activity or affect fetal development. There is insufficient safety data for use during pregnancy or breastfeeding. Women who are pregnant, trying to conceive, or nursing should not use this herb. Consult a qualified healthcare provider for pregnancy-safe alternatives for managing fever or sore throat.
What is Commelina communis used for in herbal medicine?
Commelina communis, also known as Asiatic dayflower, is used in Traditional Chinese Medicine to clear heat, detoxify the body, and manage fever and sore throat. The herb has been traditionally employed for its antiviral properties and to treat inflammatory conditions. Active compounds include commelinin, flavonoids, phenolics, and polysaccharides. Evidence level C indicates that while traditional use is well-established, clinical research remains limited. Consult a qualified practitioner for appropriate use and diagnosis.
What are the side effects of Commelina communis?
Commelina communis is generally well tolerated when used at recommended doses. No serious adverse effects have been reported in traditional use. However, the herb is contraindicated in individuals with 'cold deficiency' according to TCM principles, as its cooling properties may worsen this condition. As with any herb, allergic reactions are possible. Discontinue use if you experience any unusual symptoms and consult a healthcare provider. Evidence level C reflects limited safety data from clinical studies.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Commelina communis, also known as dayflower or Yazhicao, is a plant used in traditional medicine for treating diabetes, obesity, and infections [PMID:10418330, 39241582].
Contexte
Commelina communis (dayflower) is a widely distributed plant in global tropics and is often characterized as an invasive weed in corn and soybean fields [PMID:39592924, 34961156]. It is recognized as a metallophyte with high drought resistance and the ability to hyperaccumulate heavy metals [PMID:33365657, 34442769].
Usages traditionnels
It has been used as a traditional herbal medicine for the treatment of diabetes, obesity, and infections [PMID:10418330, 39241582, 40962098].
Composés actifs
Identified compounds include pyrrolidine alkaloids (2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine/DMDP) [PMID:10418330, 18409066], piperidine alkaloids (1-deoxynojirimycin/DNJ, 1-deoxymannojirimycin, alpha-homonojirimycin) [PMID:10418330, 18409066, 27886092], flavonoid glycosides (isoquercitrin, orientin, vitexin, isoorientin, isorhamnetin-3-O-rutinoside, isorhamnetin-3-O-beta-D-glucoside, glucoluteolin, chrysoriol-7-O-beta-D-glucoside, swertisin, and flavocommelin) [PMID:18409066], acidic glycoproteins (CCW-4 and CCW-5) [PMID:40962098], and an indigestible arabinoglucuronoxylan polysaccharide (CCB-3) [PMID:39241582].
Mécanisme d'action
The herb's components exhibit alpha-glucosidase inhibitory activity [PMID:10418330, 18409066]. Anti-inflammatory effects are mediated via modulation of the Nuclear Factor-kappaB (NF-kappaB) pathway, specifically decreasing phosphorylation of I-kappaB-alpha and intranuclear transition of the p65 subunit [PMID:35250385]. Additionally, it may alleviate septic-ALI by modulating the intestine microbiota to reduce TMAO/NLRP3 signaling [PMID:38810555].
Preuves cliniques
Preuve DInfluenza virus infection (mice)
Homonojirimycin (HNJ) improved survival rate, prolonged mean survival time, reduced lung virus yields, and modulated immune responses by increasing IFN-gamma and IL-10 while decreasing TNF-alpha and IL-6 [PMID:23746956].
Preuve DSeptic-ALI (experimental)
YZC extract inhibited excessive inflammation and alleviated septic-ALI [PMID:38810555].
Preuve DInflammation (murine macrophages)
Extract (CCE) decreased LPS-induced levels of NO, TNF-alpha, IL-1beta, and IL-6 [PMID:35250385].
Preuve DBacterial infections (in vitro)
Methanol-phase extract showed a 58.33% inhibition rate against 24 common pathogenic bacteria by disrupting cell integrity (increasing surface hydrophobicity and membrane permeability) [PMID:36840240].
Sécurité et effets indésirables
In vitro studies on murine macrophages showed that CCE treatment did not affect cell viability even at a concentration of 1.5 mg/mL [PMID:35250385].
Synthèse des preuves
The current evidence is based primarily on in vitro studies and animal models (Level D), demonstrating potential antiviral, anti-inflammatory, antibacterial, and antihyperglycemic activities. No human clinical trials were provided in the source abstracts.
Sources PubMed
1.PMID: 23746956 (2013) — Protective effect of homonojirimycin from Commelina communis (dayflower) on influenza virus infection in mice. · Phytomedicine : international journal of phytotherapy and phytopharmacology
2.PMID: 39592924 (2024) — Selection and validation of reference genes for qRT-PCR normalization in dayflower (Commelina communis) based on the transcriptome profiling. · BMC plant biology
3.PMID: 22783075 (2011) — First Report of Stem Rot on Asiatic Dayflower (Commelina communis L.) Caused by Sclerotium rolfsii in Korea. · Mycobiology
5.PMID: 38810555 (2024) — Multi-metabolomics and intestine microbiome analysis: YZC extract ameliorates septic-ALI by modulating intestine microbiota to reduce TMAO/NLRP3 signaling.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
· Phytomedicine : international journal of phytotherapy and phytopharmacology
6.PMID: 18409066 (2008) — Antioxidant constituents in the dayflower (Commelina communis L.) and their alpha-glucosidase-inhibitory activity. · Journal of natural medicines
11.PMID: 21628272 (2009) — Floral organogenesis and the developmental basis for pollinator deception in the asiatic dayflower, Commelina communis (Commelinaceae). · American journal of botany
12.PMID: 39241582 (2024) — Structural characterization and Bacteroides proliferation promotion activity of a novel homogeneous arabinoglucuronoxylan from Commelina communis L. · Bioorganic chemistry
13.PMID: 37996971 (2024) — Trait variation along an urban-rural gradient in Asian dayflower: the contribution of phenotypic plasticity and genetic divergence. · Plant biology (Stuttgart, Germany)
14.PMID: 23530829 (2013) — Homonojirimycin, an alkaloid from dayflower inhibits the growth of influenza A virus in vitro. · Acta virologica
15.PMID: 34961156 (2021) — High Antioxidant Ability Confer Resistance to Atrazine in Commelina communis L. · Plants (Basel, Switzerland)
16.PMID: 40962098 (2025) — Isolation, structural characterization, and anticomplement activity of two glycoproteins derived from Commelina communis L. · International journal of biological macromolecules
17.PMID: 36464365 (2022) — PsbA gene over-expression and enhanced metabolism conferring resistance to atrazine in Commelina communis. · Pesticide biochemistry and physiology
18.PMID: 33365657 (2019) — The chloroplast genome sequence of Commelina communis (Commelinaceae). · Mitochondrial DNA. Part B, Resources
19.PMID: 34442769 (2021) — Deciphering the Endophytic and Rhizospheric Microbial Communities of a Metallophyte Commelina communis in Different Cu-Polluted Soils. · Microorganisms
20.PMID: 31323838 (2019) — Allelopathic and Autotoxic Effects of Medicago sativa-Derived Allelochemicals. · Plants (Basel, Switzerland)
21.PMID: 21706139 (2011) — ABA signaling in stomatal guard cells: lessons from Commelina and Vicia. · Journal of plant research
22.PMID: 11299391 (2001) — Abscisic acid-induced actin reorganization in guard cells of dayflower is mediated by cytosolic calcium levels and by protein kinase and protein phosphatase activities. · Plant physiology
23.PMID: 36725225 (2023) — [Quality evaluation of Commelina communis from different origins based on multicomponent content determination combined with chemometrics]. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
24.PMID: 34694309 (2021) — Strategies used by nature to fix the red, purple and blue colours in plants: a physical chemistry approach. · Physical chemistry chemical physics : PCCP
25.PMID: 38384819 (2024) — Habitat diversification associated with urban development has a little effect on genetic structure in the annual native plant Commelina communis in an East Asian megacity. · Ecology and evolution
27.PMID: 35250385 (2022) — Treatment with Commelina communis Extract Exerts Anti-inflammatory Effects in Murine Macrophages via Modulation of the Nuclear Factor-κB Pathway. · Mediators of inflammation
28.PMID: 1843407 (1991) — Visualisation and measurement of the calcium message in guard cells. · Symposia of the Society for Experimental Biology
29.PMID: 23007596 (2013) — Measurement of cytosolic-free Ca²⁺ in plant tissue. · Methods in molecular biology (Clifton, N.J.)