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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cycas revoluta
Un cycad fossile vivant ; les graines sont transformées pour obtenir de la fécule de sago alimentaire ; toutes les parties sont toxiques sauf traitement spécial.
Cycas revoluta, a primitive gymnosperm known as sago palm, is primarily recognized for its toxic cycasin compound and historical use as a processed starch food source. Its key active compounds include cycasin, methylazoxymethanol (MAM), and tannins, which contribute to its neurotoxic and carcinogenic properties. Modern research focuses on its role in carcinogenesis and neurodegeneration, particularly in relation to ALS-like disease.
Cycasin, a glucoside, is hydrolyzed to methylazoxymethanol (MAM), a potent alkylating agent that causes DNA damage and initiates carcinogenesis. MAM also acts as a neurotoxin by inducing oxidative stress and excitotoxicity, potentially affecting glutamate receptors and mitochondrial function. Tannins may contribute to gastrointestinal irritation and liver toxicity. The neurotoxic effects are linked to the development of neurodegenerative conditions resembling amyotrophic lateral sclerosis (ALS) through mechanisms involving oxidative damage and protein aggregation.
Un cycad fossile vivant ; les graines sont transformées pour obtenir de la fécule de sago alimentaire ; toutes les parties sont toxiques sauf traitement spécial.
Cycas revoluta, a primitive gymnosperm known as sago palm, is primarily recognized for its toxic cycasin compound and historical use as a processed starch food source. Its key active compounds include cycasin, methylazoxymethanol (MAM), and tannins, which contribute to its neurotoxic and carcinogenic properties. Modern research focuses on its role in carcinogenesis and neurodegeneration, particularly in relation to ALS-like disease.
Cycasin, a glucoside, is hydrolyzed to methylazoxymethanol (MAM), a potent alkylating agent that causes DNA damage and initiates carcinogenesis. MAM also acts as a neurotoxin by inducing oxidative stress and excitotoxicity, potentially affecting glutamate receptors and mitochondrial function. Tannins may contribute to gastrointestinal irritation and liver toxicity. The neurotoxic effects are linked to the development of neurodegenerative conditions resembling amyotrophic lateral sclerosis (ALS) through mechanisms involving oxidative damage and protein aggregation.