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CO
Not CommonGénéré par IA
Cydonia Oblonga Herb
Cydonia oblonga
Astringent contre la diarrhée dans la médecine populaire du Moyen-Orient
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Cydonia oblonga (quince) is a medicinal plant of the Rosaceae family recognized for its antioxidant, anti-inflammatory, and antimicrobial properties [PMID: 27445806, PMID: 35661598]. It is used in various traditional medicines to treat conditions such as diabetes, cancer, and infections [PMID: 36262168, PMID: 27445806].
Contexte
Cydonia oblonga, commonly known as quince, is a monotypic genus in the Rosaceae family native to the Mediterranean region [PMID: 36262168, PMID: 35661598]. It is cultivated globally and used both as a food source (processed into jams and jellies) and for its healing properties [PMID: 37049829, PMID: 35661598].
Usages traditionnels
Used in traditional medicine to prevent or treat ailments including cancer, diabetes, hepatitis, ulcers, respiratory infections, and urinary infections [PMID: 27445806, PMID: 36262168]. In Iranian Traditional Medicine (ITM), it is indicated for treating dysuria secondary to inflammatory disorders and urethral moisturizing layer defects [PMID: 25637157]. It is also utilized in traditional Uighur medicine [PMID: 38878943].
Composés actifs
The plant is rich in secondary metabolites including phenolics, flavonoids, steroids, terpenoids, tannins, sugars, organic acids, glycosides, and megastigmane glycosides [PMID: 27445806, PMID: 38878943]. It also contains vitamins, minerals, fibers, pectin, and a polysaccharide mucilage (glucuronoxylan) extruded from the seeds [PMID: 35661598, PMID: 27445806].
Mécanisme d'action
Cydonia oblonga exhibits antioxidant and anti-inflammatory activities by inhibiting the secretion of cytokines such as TNF-α and IL-6 in RAW264.7 cells [PMID: 38878943]. Pulp callus extracts have been shown to inhibit oxidative stress and inflammation in injured cells by affecting the expression of genes including iNOS, IL-6, IL-1β, ikBα, and ICAM [PMID: 37237942]. It also demonstrates α-glucosidase inhibitory activity [PMID: 36559019].
Preuves cliniques
Preuve BSkin Moisturizing
A 4% fresh fruit extract emulgel was evaluated in a randomized single-blind study of 13 female volunteers, showing potential for amplifying facial skin moisturizing [PMID: 38131920]
Preuve CCardiovascular Risk Factors
Review of 12 animal or in vitro studies indicates positive effects on blood pressure, diabetes, glucose metabolism, lipid profile, and thrombosis [PMID: 36262168]
Preuve DUrolithiasis (Kidney Stones)
Leaf extracts demonstrated antioxidant properties and litholytic effects on experimentally prepared calcium oxalate kidney stones in an in vitro model [PMID: 38597997]
Sécurité et effets indésirables
Case reports indicate that allergy to quince can occur [PMID: 24176469].
Synthèse des preuves
The majority of evidence is based on in vitro studies, animal models, and literature reviews (Level C and D), with very limited low-powered clinical data (Level B) regarding cosmetic application.
Sources PubMed
1.PMID: 36262168 (2022) — Cardiovascular Effects of Cydonia oblonga Miller (Quince). · Evidence-based complementary and alternative medicine : eCAM
2.PMID: 27445806 (2016) — Cydonia oblonga M., A Medicinal Plant Rich in Phytonutrients for Pharmaceuticals. · Frontiers in pharmacology
3.PMID: 24176469 (2015) — Allergy to quince. · Allergologia et immunopathologia
4.PMID: 35661598 (2022) — Quince fruit Cydonia oblonga Mill nutritional composition, antioxidative properties, health benefits and consumers preferences towards some industrial quince products: A review. · Food chemistry
5.PMID: 37049829 (2023) — Changes in Physicochemical and Bioactive Properties of Quince (Cydonia oblonga Mill.) and Its Products.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
10.PMID: 38131920 (2023) — Gauging Quince Phytonutrients and Its 4% Emulgel Effect on Amplifying Facial Skin Moisturizing Potential. · Gels (Basel, Switzerland)
11.PMID: 37896205 (2023) — Cydonia oblonga-Seed-Mucilage-Based pH-Sensitive Graft Copolymer for Controlled Drug Delivery-In Vitro and In Vivo Evaluation. · Pharmaceutics
12.PMID: 36444248 (2022) — Effect of geographical location, processing and simulated digestion on antioxidant characteristics of quince (Cydonia oblonga). · Heliyon
13.PMID: 37929101 (2023) — Utilization of Quince (Cydonia oblonga) Peel and Exploration of Its Metabolite Profiling and Cardioprotective Potential Against Doxorubicin-Induced Cardiotoxicity in Wistar Rats. · ACS omega
14.PMID: 38878943 (2024) — Megastigmane glycosides from the traditional Uighur medicine Cydonia oblonga Mill. · Phytochemistry
15.PMID: 38876235 (2024) — Stimuli-responsive glucuronoxylan polysaccharide from quince seeds for biomedical, food packaging, and environmental applications. · International journal of biological macromolecules
16.PMID: 38597997 (2024) — Antioxidant activity and Inhibitory effects of Cydonia oblonga Miller. leaves extracts against calcium oxalate stones. · Urolithiasis
17.PMID: 37763199 (2023) — The Possibility of Using Fruit-Bearing Plants of Temperate Climate in the Treatment and Prevention of Diabetes. · Life (Basel, Switzerland)
18.PMID: 36559019 (2022) — Component Characterization, In Vitro Activities and Molecular Mechanism of Cydonia oblonga Mill. against Diabetic. · Pharmaceuticals (Basel, Switzerland)
19.PMID: 38474645 (2024) — Pulp or Peel? Comparative Analysis of the Phytochemical Content and Selected Cosmetic-Related Properties of Annona cherimola L., Diospyros kaki Thumb., Cydonia oblonga Mill. and Fortunella margarita Swingle Pulp and Peel Extracts. · Molecules (Basel, Switzerland)
20.PMID: 38247495 (2024) — Quinces (Cydonia oblonga, Chaenomeles sp., and Pseudocydonia sinensis) as Medicinal Fruits of the Rosaceae Family: Current State of Knowledge on Properties and Use. · Antioxidants (Basel, Switzerland)