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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Daphne genkwa
Arbustre caducifolié utilisé en TCM comme un puissant laxatif et pour expulser l'eau accumulée, à utiliser avec prudence pour l'œdème et l'épanchement pleural.
Daphne genkwa is a deciduous shrub used in Traditional Chinese Medicine as a potent purgative and hydragogue for severe edema and pleural effusion. Its primary active compounds include the diterpenoid yuanhuacin and genkwadaphnin, which exert strong irritant and toxic effects. Due to its narrow therapeutic index and potential for severe toxicity, it is used only under strict supervision.
Yuanhuacin and genkwadaphnin are diterpenoid esters that activate protein kinase C (PKC) and stimulate intestinal peristalsis and fluid secretion, resulting in purgation. They also inhibit Na+/K+-ATPase in renal tubules, promoting diuresis. These compounds induce apoptosis in certain cancer cell lines via mitochondrial pathways, but their clinical use is limited by severe gastrointestinal and hepatotoxic effects.
Arbustre caducifolié utilisé en TCM comme un puissant laxatif et pour expulser l'eau accumulée, à utiliser avec prudence pour l'œdème et l'épanchement pleural.
Daphne genkwa is a deciduous shrub used in Traditional Chinese Medicine as a potent purgative and hydragogue for severe edema and pleural effusion. Its primary active compounds include the diterpenoid yuanhuacin and genkwadaphnin, which exert strong irritant and toxic effects. Due to its narrow therapeutic index and potential for severe toxicity, it is used only under strict supervision.
Yuanhuacin and genkwadaphnin are diterpenoid esters that activate protein kinase C (PKC) and stimulate intestinal peristalsis and fluid secretion, resulting in purgation. They also inhibit Na+/K+-ATPase in renal tubules, promoting diuresis. These compounds induce apoptosis in certain cancer cell lines via mitochondrial pathways, but their clinical use is limited by severe gastrointestinal and hepatotoxic effects.