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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Delphinium staphisagria
Plante méditerranéenne historiquement utilisée comme insecticide et contre les parasites cutanés; très toxique.
Delphinium staphisagria (stavesacre) is a highly toxic Mediterranean plant historically employed as an insecticide and for treating skin parasites such as lice and mites. Its primary active compounds include the diterpenoid alkaloids delphinine, staphisine, and ajacine, which exhibit potent neurotoxic and cardiotoxic properties. Modern research is limited (evidence level C) and focuses on topical insecticidal applications, but internal use is lethal.
Delphinine and related alkaloids act as sodium channel agonists, binding to site 2 of voltage-gated sodium channels and prolonging channel opening, leading to persistent depolarization and repetitive firing in neurons and muscle cells. This results in neurotoxicity, paralysis, and cardiac arrhythmias. Staphisine and ajacine also exhibit anticholinergic and local irritant effects, contributing to the plant's insecticidal and anti-parasitic activity. Tannins provide astringent properties that may aid in topical parasite removal.
Plante méditerranéenne historiquement utilisée comme insecticide et contre les parasites cutanés; très toxique.
Delphinium staphisagria (stavesacre) is a highly toxic Mediterranean plant historically employed as an insecticide and for treating skin parasites such as lice and mites. Its primary active compounds include the diterpenoid alkaloids delphinine, staphisine, and ajacine, which exhibit potent neurotoxic and cardiotoxic properties. Modern research is limited (evidence level C) and focuses on topical insecticidal applications, but internal use is lethal.
Delphinine and related alkaloids act as sodium channel agonists, binding to site 2 of voltage-gated sodium channels and prolonging channel opening, leading to persistent depolarization and repetitive firing in neurons and muscle cells. This results in neurotoxicity, paralysis, and cardiac arrhythmias. Staphisine and ajacine also exhibit anticholinergic and local irritant effects, contributing to the plant's insecticidal and anti-parasitic activity. Tannins provide astringent properties that may aid in topical parasite removal.