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Succisa pratensis
Herbe des prairies européennes historiquement utilisée contre la peste, les fièvres et comme cicatrisant, importante dans la médecine populaire celtique et irlandaise.
Devil's Bit Scabious (Succisa pratensis) is a European meadow herb historically used in Celtic and Irish folk medicine for plague, fevers, and wound healing. Modern research indicates anti-inflammatory, antimicrobial, and antioxidant properties attributed to its iridoid glycosides (e.g., loganin, sweroside) and flavonoids. It is primarily used as an expectorant and for mild inflammatory conditions, with evidence limited to preliminary studies.
The iridoid glycosides loganin and sweroside exhibit anti-inflammatory activity by inhibiting NF-κB and COX-2 pathways, reducing pro-inflammatory cytokines. Caffeoyl glycosides and flavonoids contribute antioxidant effects via free radical scavenging and upregulation of endogenous antioxidant enzymes. Antimicrobial action is attributed to disruption of bacterial cell membranes and inhibition of biofilm formation. Expectorant effects may involve stimulation of bronchial secretions via iridoid-mediated modulation of mucociliary clearance.
Herbe des prairies européennes historiquement utilisée contre la peste, les fièvres et comme cicatrisant, importante dans la médecine populaire celtique et irlandaise.
Devil's Bit Scabious (Succisa pratensis) is a European meadow herb historically used in Celtic and Irish folk medicine for plague, fevers, and wound healing. Modern research indicates anti-inflammatory, antimicrobial, and antioxidant properties attributed to its iridoid glycosides (e.g., loganin, sweroside) and flavonoids. It is primarily used as an expectorant and for mild inflammatory conditions, with evidence limited to preliminary studies.
The iridoid glycosides loganin and sweroside exhibit anti-inflammatory activity by inhibiting NF-κB and COX-2 pathways, reducing pro-inflammatory cytokines. Caffeoyl glycosides and flavonoids contribute antioxidant effects via free radical scavenging and upregulation of endogenous antioxidant enzymes. Antimicrobial action is attributed to disruption of bacterial cell membranes and inhibition of biofilm formation. Expectorant effects may involve stimulation of bronchial secretions via iridoid-mediated modulation of mucociliary clearance.