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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Alstonia scholaris
Un arbre tropical asiatique dont l'écorce est utilisée en médecine ayurvédique et philippine pour la fièvre, le paludisme et les affections digestives.
Dita bark (Alstonia scholaris) is a tropical Asian tree bark used in Ayurvedic and Filipino traditional medicine for fever, malaria, and digestive conditions. Its primary active compounds include the indole alkaloids echitamine, alstonine, ditamine, and picrinine, which contribute to its antimalarial, antidiarrheal, analgesic, and antidiabetic properties. Evidence is limited (Level C) but supports its traditional uses.
Alstonine exhibits antimalarial activity by inhibiting heme polymerization, a process essential for the survival of Plasmodium parasites. Echitamine demonstrates anti-inflammatory and analgesic effects through modulation of cyclooxygenase (COX) enzymes and inhibition of prostaglandin synthesis. The antidiarrheal action may involve anticholinergic and spasmolytic effects on gastrointestinal smooth muscle, while antidiabetic activity is attributed to alpha-glucosidase inhibition and enhanced insulin sensitivity. These mechanisms are supported by in vitro and limited in vivo studies.
Un arbre tropical asiatique dont l'écorce est utilisée en médecine ayurvédique et philippine pour la fièvre, le paludisme et les affections digestives.
Dita bark (Alstonia scholaris) is a tropical Asian tree bark used in Ayurvedic and Filipino traditional medicine for fever, malaria, and digestive conditions. Its primary active compounds include the indole alkaloids echitamine, alstonine, ditamine, and picrinine, which contribute to its antimalarial, antidiarrheal, analgesic, and antidiabetic properties. Evidence is limited (Level C) but supports its traditional uses.
Alstonine exhibits antimalarial activity by inhibiting heme polymerization, a process essential for the survival of Plasmodium parasites. Echitamine demonstrates anti-inflammatory and analgesic effects through modulation of cyclooxygenase (COX) enzymes and inhibition of prostaglandin synthesis. The antidiarrheal action may involve anticholinergic and spasmolytic effects on gastrointestinal smooth muscle, while antidiabetic activity is attributed to alpha-glucosidase inhibition and enhanced insulin sensitivity. These mechanisms are supported by in vitro and limited in vivo studies.