Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
A 30-day randomized double-blind trial indicated the efficacy of a topical formulation of D. ammoniacum gum extract in treating melasma [PMID:33964194]
In a rat model, topical application of 5%, 10%, and 20% gum extract ointments significantly decreased wound areas compared to controls [PMID:36240871]
Aqueous gum solution showed significant anticonvulsant activity in PTZ-induced mice models [PMID:28255314] and anti-epileptogenic effects in rats [PMID:32851611], although another cellular model suggested it might increase neuronal excitability [PMID:29881430]
Essential oil (50-100 mg/kg) improved memory impairment induced by D-galactose and scopolamine in mice [PMID:33680015]; seed extracts also showed nootropic effects in mice [PMID:33669503]
Essential oil and aqueous extracts reduced viability of A549 cancer cells [PMID:35983460]; gum extracts affected HT-29 colon cancer cells [PMID:37724146]; and Sal-Ammoniac extract inhibited Lewis lung cancer cell proliferation in vitro and in vivo [PMID:18619270]
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 34848241 (2022) — Purification, structural characterization and antioxidant activity of a new arabinogalactan from Dorema ammoniacum gum. · International journal of biological macromolecules
- 2.PMID: 36240871 (2022) — Determination of the effectiveness of Dorema ammoniacum gum on wound healing: an experimental study. · Journal of wound care
- 3.PMID: 35156874 (2023) — Composition of the essential oil of different plant organs in Dorema ammoniacum D. Don and Dorema aucheri Boiss. accessions collected from Iran. · Natural product research
- 4.PMID: 28255314 (2017) — Anticonvulsant activity of Dorema ammoniacum gum: evidence for the involvement of benzodiazepines and opioid receptors. · Research in pharmaceutical sciences
- 5.PMID: 29881430