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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Dysphania ambrosioides
Herbe aromatique piquante utilisée par les Aztèques et à travers les Amériques contre les vers intestinaux et comme accompagnement traditionnel des plats à base de haricots pour réduire les flatulences.
Epazote (Dysphania ambrosioides) is a pungent aromatic herb traditionally used by Aztec and other Mesoamerican cultures as an anthelmintic and carminative, particularly to reduce flatulence from bean dishes. Its primary active compound, ascaridole, is a peroxide that exhibits anthelmintic, antimicrobial, and antifungal properties, while p-cymene and limonene contribute to its carminative and digestive effects. Modern evidence is limited (Level C), supporting its traditional uses but also highlighting significant toxicity risks, especially from the essential oil.
Ascaridole, a bicyclic monoterpene peroxide, exerts anthelmintic effects by generating reactive oxygen species that damage the tegument and intestinal cells of parasitic worms, leading to paralysis and expulsion. The compound also inhibits acetylcholinesterase in parasites, disrupting neuromuscular function. P-cymene and limonene act as carminatives by relaxing gastrointestinal smooth muscle and reducing gas formation, possibly via modulation of serotonin (5-HT3) receptors and inhibition of gas-producing bacteria. Flavonoids contribute antioxidant and anti-inflammatory effects, while the essential oil's high ascaridole content can induce hepatotoxicity through oxidative stress and neurotoxicity via GABA receptor antagonism.
Herbe aromatique piquante utilisée par les Aztèques et à travers les Amériques contre les vers intestinaux et comme accompagnement traditionnel des plats à base de haricots pour réduire les flatulences.
Epazote (Dysphania ambrosioides) is a pungent aromatic herb traditionally used by Aztec and other Mesoamerican cultures as an anthelmintic and carminative, particularly to reduce flatulence from bean dishes. Its primary active compound, ascaridole, is a peroxide that exhibits anthelmintic, antimicrobial, and antifungal properties, while p-cymene and limonene contribute to its carminative and digestive effects. Modern evidence is limited (Level C), supporting its traditional uses but also highlighting significant toxicity risks, especially from the essential oil.
Ascaridole, a bicyclic monoterpene peroxide, exerts anthelmintic effects by generating reactive oxygen species that damage the tegument and intestinal cells of parasitic worms, leading to paralysis and expulsion. The compound also inhibits acetylcholinesterase in parasites, disrupting neuromuscular function. P-cymene and limonene act as carminatives by relaxing gastrointestinal smooth muscle and reducing gas formation, possibly via modulation of serotonin (5-HT3) receptors and inhibition of gas-producing bacteria. Flavonoids contribute antioxidant and anti-inflammatory effects, while the essential oil's high ascaridole content can induce hepatotoxicity through oxidative stress and neurotoxicity via GABA receptor antagonism.