Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
MC
Not CommonRésumée par IA
Melisse citronnée
Lippia alba
Anxiété et insomnie dans la médecine populaire brésilienne et mexicaine
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Lippia alba, known as erva-cidreira, is an aromatic shrub used in Brazilian folk medicine primarily for its sedative, analgesic, and antihypertensive properties [PMID:18207682, PMID:16784826, PMID:39381914].
Contexte
Lippia alba (Mill.) N.E. Brown is a phenotypically variable tropical shrub found in practically all regions of Brazil [PMID:16784826, PMID:33760982]. It is characterized by significant variability in morphology and chemical composition of its essential oils [PMID:16784826].
Usages traditionnels
Traditionally used in Brazil as a remedy for digestive and respiratory ailments, as a sedative, an antihypertensive, an antispasmodic, and an antidyspeptic [PMID:18207682, PMID:36181984]. It is also used in teas to treat pain and inflammatory diseases [PMID:38897034].
Composés actifs
The plant contains essential oils with various chemotypes (e.g., myrcene-citral) and non-volatile compounds including iridoids, phenylethanoids, flavone glycosides, biflavonoids, tannins, and anthocyanins [PMID:18207682, PMID:16784826, PMID:37364681]. Specific identified compounds include citral, limonene, linalool, geraniol, geranial, neral, and acteoside [PMID:16784826, PMID:38897034, PMID:39381914, PMID:40143196].
Mécanisme d'action
Lippia alba essential oil and its constituents citral and limonene cause dose-dependent relaxation of rat uterine muscle [PMID:30447181]. The essential oil also demonstrates inhibitory activity on LPS-stimulated Nitric Oxide (NO) production in RAW 264.7 macrophages [PMID:29605588].
Preuves cliniques
Preuve CAnxiety and Insomnia
Partial positive results have been obtained regarding sedative and anxiolytic activities [PMID:18207682].
Preuve DHypertension
Methanolic extract of L. alba showed significant hypotensive effects on systolic, diastolic, and mean arterial pressure in normotensive rats [PMID:39381914].
Preuve DPain and Inflammation
Essential oil and geraniol demonstrated antinociceptive and anti-inflammatory activities in mouse models [PMID:38897034].
Preuve CBreast Cancer
Review suggests potential anticancer effects on breast cancer cells and synergy with conventional treatments [PMID:38261655].
Preuve DSchistosomiasis
In vitro exposure to L. alba essential oil reduced adult S. mansoni worm viability by approximately 60% after 24 hours [PMID:35364048].
Sécurité et effets indésirables
Genotoxic action was observed via micronucleus and comet assays at doses of 100, 200, and 300 mg/kg in fish and mammals, with greater damage seen in fish [PMID:29605588].
Interactions médicamenteuses
L. alba is used by patients in anticoagulation clinics, but there is a lack of studies supporting the safety of its concomitant use with warfarin [PMID:36181984].
Synthèse des preuves
The evidence is primarily based on ethnopharmacological reviews and in vitro or animal studies (Level C and D). Clinical trials in humans are lacking, particularly for its use as a sedative [PMID:18207682].
Sources PubMed
1.PMID: 18207682 (2008) — Ethnopharmacology of Lippia alba. · Journal of ethnopharmacology
2.PMID: 38261655 (2024) — Ippia Alba Essential Oil: A Promising Complementary Therapy for Breast Cancer. · Chemistry & biodiversity
3.PMID: 16784826 (2006) — Ethnopharmacological study of two Lippia species from Oriximiná, Brazil. · Journal of ethnopharmacology
4.PMID: 36181984 (2023) — Antithrombotic potential of Lippia alba: A mechanistic approach. · Journal of ethnopharmacology
5.PMID: 35364048 (2022) — Lippia alba and Lippia gracilis essential oils affect the viability and oviposition of Schistosoma mansoni. · Acta tropica
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 40143196 (2025) — Unraveling the Neuropharmacological Properties of Lippia alba: A Scientometric Approach. · Pharmaceuticals (Basel, Switzerland)
7.PMID: 30447181 (2019) — Tocolytic activity of the Lippia alba essential oil and its major constituents, citral and limonene, on the isolated uterus of rats. · Chemico-biological interactions
8.PMID: 38897034 (2024) — Lippia alba essential oil: A powerful and valuable antinociceptive and anti-inflammatory medicinal plant from Brazil. · Journal of ethnopharmacology
9.PMID: 39381914 (2025) — In vivo hypotensive effect of a chemically characterised extract from the leaves of Lippia alba (Mill.) N.E.Br. · Natural product research
10.PMID: 37364681 (2023) — Comparative analysis indicates a simple protocol for DNA extraction of the aromatic plant Lippia alba. · Analytical biochemistry
11.PMID: 33760982 (2022) — Chromosomal view of Lippia alba, a tropical polyploid complex under genome stabilization process. · Protoplasma
12.PMID: 29605588 (2018) — Genotoxic effect of Lippia alba (Mill.) N. E. Brown essential oil on fish (Oreochromis niloticus) and mammal (Mus musculus). · Environmental toxicology and pharmacology