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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Gaultheria procumbens
A North American woodland plant yielding oil of wintergreen (methyl salicylate); a topical pain reliever with aspirin-like activity; widely used for muscle and joint pain.
Gaultheria procumbens (wintergreen) is a North American woodland plant whose essential oil is rich in methyl salicylate, a topical analgesic and anti-inflammatory agent used for muscle and joint pain. Its primary active compound acts as a counterirritant and is metabolized to salicylic acid, providing aspirin-like effects locally. The herb also contains gaultherin, arbutin, and terpenes that contribute to its traditional use in Native American medicine for rheumatic pain, headache, and wound care.
Methyl salicylate, the primary active compound, is a prodrug that is hydrolyzed by esterases in the skin and systemic circulation to salicylic acid, which inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis and thereby decreasing pain and inflammation. Additionally, methyl salicylate acts as a counterirritant by activating transient receptor potential (TRP) channels, such as TRPV1 and TRPA1, on sensory neurons, leading to desensitization and local analgesia. The compound gaultherin may also contribute to anti-inflammatory effects through modulation of nuclear factor-kappa B (NF-κB) signaling, while arbutin provides mild antimicrobial and antioxidant properties.
A North American woodland plant yielding oil of wintergreen (methyl salicylate); a topical pain reliever with aspirin-like activity; widely used for muscle and joint pain.
Gaultheria procumbens (wintergreen) is a North American woodland plant whose essential oil is rich in methyl salicylate, a topical analgesic and anti-inflammatory agent used for muscle and joint pain. Its primary active compound acts as a counterirritant and is metabolized to salicylic acid, providing aspirin-like effects locally. The herb also contains gaultherin, arbutin, and terpenes that contribute to its traditional use in Native American medicine for rheumatic pain, headache, and wound care.
Methyl salicylate, the primary active compound, is a prodrug that is hydrolyzed by esterases in the skin and systemic circulation to salicylic acid, which inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis and thereby decreasing pain and inflammation. Additionally, methyl salicylate acts as a counterirritant by activating transient receptor potential (TRP) channels, such as TRPV1 and TRPA1, on sensory neurons, leading to desensitization and local analgesia. The compound gaultherin may also contribute to anti-inflammatory effects through modulation of nuclear factor-kappa B (NF-κB) signaling, while arbutin provides mild antimicrobial and antioxidant properties.