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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Zingiber zerumbet
Wild Southeast Asian and Pacific ginger with bitter edible rhizome used in Hawaiian, Malaysian, and Indonesian medicine for pain and inflammation.
Zingiber zerumbet, commonly known as wild ginger or shampoo ginger, is a Southeast Asian and Pacific medicinal plant whose rhizome contains the bioactive sesquiterpene zerumbone. It is traditionally used for pain, inflammation, and gastrointestinal complaints, and modern research supports its anti-inflammatory, anticancer, and antimicrobial activities. Key active compounds include zerumbone, zerumbol, humulene, camphene, and flavonoids.
Zerumbone, the primary bioactive constituent, exerts anti-inflammatory effects by inhibiting the NF-κB pathway, reducing COX-2 and iNOS expression, and suppressing pro-inflammatory cytokines such as TNF-α and IL-6. It also activates the Nrf2/ARE pathway, enhancing antioxidant defenses. In cancer models, zerumbone induces apoptosis via caspase activation and mitochondrial dysfunction, and inhibits proliferation by modulating PI3K/Akt and MAPK signaling. Antimicrobial actions involve disruption of bacterial cell membranes and inhibition of biofilm formation.
Wild Southeast Asian and Pacific ginger with bitter edible rhizome used in Hawaiian, Malaysian, and Indonesian medicine for pain and inflammation.
Zingiber zerumbet, commonly known as wild ginger or shampoo ginger, is a Southeast Asian and Pacific medicinal plant whose rhizome contains the bioactive sesquiterpene zerumbone. It is traditionally used for pain, inflammation, and gastrointestinal complaints, and modern research supports its anti-inflammatory, anticancer, and antimicrobial activities. Key active compounds include zerumbone, zerumbol, humulene, camphene, and flavonoids.
Zerumbone, the primary bioactive constituent, exerts anti-inflammatory effects by inhibiting the NF-κB pathway, reducing COX-2 and iNOS expression, and suppressing pro-inflammatory cytokines such as TNF-α and IL-6. It also activates the Nrf2/ARE pathway, enhancing antioxidant defenses. In cancer models, zerumbone induces apoptosis via caspase activation and mitochondrial dysfunction, and inhibits proliferation by modulating PI3K/Akt and MAPK signaling. Antimicrobial actions involve disruption of bacterial cell membranes and inhibition of biofilm formation.