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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cynara cardunculus
The leaf extract of the globe artichoke (not the edible head) is a well-studied choleretic; cynarin and luteolin stimulate bile production, improve fat digestion, and lower cholesterol.
Globe artichoke (Cynara cardunculus) leaf extract is a clinically studied choleretic and hypolipidemic agent, primarily used to stimulate bile production, improve fat digestion, and lower LDL cholesterol. Its key active compounds include cynarin, luteolin, chlorogenic acid, and cynaropicrin, which contribute to its hepatoprotective and digestive benefits.
Artichoke leaf extract exerts choleretic effects primarily through cynarin and luteolin, which stimulate bile acid synthesis and secretion by upregulating cholesterol 7α-hydroxylase (CYP7A1) and enhancing gallbladder contraction via cholecystokinin receptor activation. The flavonoids luteolin and chlorogenic acid inhibit HMG-CoA reductase, reducing hepatic cholesterol synthesis, while cynaropicrin exhibits anti-inflammatory and antioxidant properties by modulating NF-κB and Nrf2 pathways. These combined actions improve lipid metabolism, reduce LDL oxidation, and alleviate dyspeptic symptoms.
The leaf extract of the globe artichoke (not the edible head) is a well-studied choleretic; cynarin and luteolin stimulate bile production, improve fat digestion, and lower cholesterol.
Globe artichoke (Cynara cardunculus) leaf extract is a clinically studied choleretic and hypolipidemic agent, primarily used to stimulate bile production, improve fat digestion, and lower LDL cholesterol. Its key active compounds include cynarin, luteolin, chlorogenic acid, and cynaropicrin, which contribute to its hepatoprotective and digestive benefits.
Artichoke leaf extract exerts choleretic effects primarily through cynarin and luteolin, which stimulate bile acid synthesis and secretion by upregulating cholesterol 7α-hydroxylase (CYP7A1) and enhancing gallbladder contraction via cholecystokinin receptor activation. The flavonoids luteolin and chlorogenic acid inhibit HMG-CoA reductase, reducing hepatic cholesterol synthesis, while cynaropicrin exhibits anti-inflammatory and antioxidant properties by modulating NF-κB and Nrf2 pathways. These combined actions improve lipid metabolism, reduce LDL oxidation, and alleviate dyspeptic symptoms.