Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
In healthy non-diabetic human subjects, the fruit demonstrated a low glycemic index (5.34) with modest hypoglycemic activity [PMID:23261731].
Ethanolic fruit extract reduced blood glucose and pancreatic MDA levels while increasing liver glycogen in STZ-induced diabetic rats [PMID:26347423]. Stem bark extract also showed antidiabetic and antihyperlipidemic properties in alloxan-induced diabetic rats [PMID:27538464].
Methanol extract of leaves provided protection against pentylenetetrazole and maximal electroshock induced seizures and showed anxiolytic activity in mice [PMID:35933940]. Fruit juice (20-30% dilutions) diminished anxiety, depression, and scopolamine-induced memory impairment in rats [PMID:33521033].
Lyophilized fruit powder (200-400 mg/kg) effectively reduced renal biomarkers, blood urea nitrogen, and creatinine in cisplatin-induced acute kidney injury rats [PMID:40291032].
Fruit extract (250-500 mg/kg) decreased serum AST, ALT, LDH, and CKMB in isoproterenol-induced myocardial injury and reduced carrageenan-induced paw edema [PMID:36861237].
Synthèse des preuves
Sources PubMed
- 1.PMID: 32320069 (2020) — Nutraceutical perspectives and value addition of phalsa (Grewia asiatica L.): A review. · Journal of food biochemistry
- 2.PMID: 34229590 (2022) — Indian Indigenous Fruits as Radioprotective Agents: Past, Present and Future. · Anti-cancer agents in medicinal chemistry
- 3.PMID: 38312640 (2024) — Phytochemical and pharmacological characteristics of phalsa (Grewia asiatica L.): A comprehensive review. · Heliyon
- 4.PMID: 36348773 (2022) — Selection of promising accessions of phalsa (Grewia asiatica L.) based on fruit-related traits. · Food science & nutrition
- 5.PMID: 37464170 (2024) — Tracking the Variations in Trace Elements, Some Nutrients, Phenolics, and Anthocyanins in Grewia asiatica L. (Phalsa) at Different Fruit Development Stages.