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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Trichosanthes kirilowii (pericarp)
TCM fruit pericarp that clears lung heat and transforms phlegm.
Gua Lou Pi (Trichosanthes kirilowii pericarp) is a traditional Chinese medicinal herb used primarily as an expectorant and anti-inflammatory agent for respiratory conditions involving phlegm-heat. Its active compounds include triterpenoids (e.g., cucurbitacins), flavonoids, and organic acids, which contribute to its ability to clear lung heat, transform phlegm, and alleviate chest tightness. Evidence is limited to pilot studies and traditional use, with preliminary data supporting expectorant and anti-inflammatory effects.
Gua Lou Pi exerts its expectorant effects by increasing respiratory tract fluid secretion and reducing mucus viscosity, likely through triterpenoid-mediated modulation of airway epithelial ion channels and mucin production. Its anti-inflammatory action involves inhibition of cyclooxygenase-2 (COX-2) and lipoxygenase pathways, reducing prostaglandin and leukotriene synthesis. Flavonoids in the herb may also suppress NF-κB activation, thereby decreasing pro-inflammatory cytokines such as IL-6 and TNF-α. Additionally, cucurbitacins have been shown to induce apoptosis in certain cancer cell lines, though this is not a primary clinical use.
TCM fruit pericarp that clears lung heat and transforms phlegm.
Gua Lou Pi (Trichosanthes kirilowii pericarp) is a traditional Chinese medicinal herb used primarily as an expectorant and anti-inflammatory agent for respiratory conditions involving phlegm-heat. Its active compounds include triterpenoids (e.g., cucurbitacins), flavonoids, and organic acids, which contribute to its ability to clear lung heat, transform phlegm, and alleviate chest tightness. Evidence is limited to pilot studies and traditional use, with preliminary data supporting expectorant and anti-inflammatory effects.
Gua Lou Pi exerts its expectorant effects by increasing respiratory tract fluid secretion and reducing mucus viscosity, likely through triterpenoid-mediated modulation of airway epithelial ion channels and mucin production. Its anti-inflammatory action involves inhibition of cyclooxygenase-2 (COX-2) and lipoxygenase pathways, reducing prostaglandin and leukotriene synthesis. Flavonoids in the herb may also suppress NF-κB activation, thereby decreasing pro-inflammatory cytokines such as IL-6 and TNF-α. Additionally, cucurbitacins have been shown to induce apoptosis in certain cancer cell lines, though this is not a primary clinical use.