Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Guiera senegalensis
Shrub widespread in the West African Sahel used in traditional medicine across Senegal, Mali, and Niger as one of the most important antiparasitic plants.
Guiera senegalensis is a shrub native to the West African Sahel, traditionally used for malaria, intestinal parasites, and respiratory infections. Its primary active compounds include ellagitannins, flavonoids, and alkaloids, which contribute to its antiplasmodial, anthelmintic, and anti-inflammatory properties. The plant is classified under evidence level C, indicating limited clinical data supporting its traditional uses.
Ellagitannins and flavonoids in Guiera senegalensis inhibit Plasmodium falciparum growth by interfering with heme polymerization and promoting oxidative stress. Tannins exhibit anthelmintic activity by binding to proteins in parasite cuticles, disrupting membrane integrity. Alkaloids and saponins may modulate inflammatory pathways via inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, reducing prostaglandin and leukotriene synthesis. Additionally, flavonoids act as antioxidants, scavenging free radicals and reducing oxidative damage in infected tissues.
Shrub widespread in the West African Sahel used in traditional medicine across Senegal, Mali, and Niger as one of the most important antiparasitic plants.
Guiera senegalensis is a shrub native to the West African Sahel, traditionally used for malaria, intestinal parasites, and respiratory infections. Its primary active compounds include ellagitannins, flavonoids, and alkaloids, which contribute to its antiplasmodial, anthelmintic, and anti-inflammatory properties. The plant is classified under evidence level C, indicating limited clinical data supporting its traditional uses.
Ellagitannins and flavonoids in Guiera senegalensis inhibit Plasmodium falciparum growth by interfering with heme polymerization and promoting oxidative stress. Tannins exhibit anthelmintic activity by binding to proteins in parasite cuticles, disrupting membrane integrity. Alkaloids and saponins may modulate inflammatory pathways via inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, reducing prostaglandin and leukotriene synthesis. Additionally, flavonoids act as antioxidants, scavenging free radicals and reducing oxidative damage in infected tissues.