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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Gynostemma pentaphyllum
A climbing vine from Asia dubbed the immortality herb, rich in gypenosides structurally similar to ginsenosides; used as a powerful adaptogen, antioxidant, and cardiovascular tonic.
Gynostemma pentaphyllum, a climbing vine native to Asia and traditionally known as the 'immortality herb,' is rich in gypenosides—saponins structurally analogous to ginsenosides—and is used as an adaptogen for stress reduction, a cardiometabolic tonic for cholesterol and triglyceride management, and an antioxidant for anti-aging support. Its bioactive compounds include gypenosides, flavonoids, and polysaccharides, which contribute to its broad therapeutic profile. Evidence is limited to pilot studies and traditional use, placing it at evidence level C.
Gypenosides modulate the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol release and enhancing stress resilience. They also activate the Nrf2/ARE pathway, upregulating antioxidant enzymes such as superoxide dismutase and catalase, and improve endothelial function by increasing nitric oxide (NO) production via eNOS activation. Additionally, gypenosides influence lipid metabolism through PPARα agonism, leading to reduced hepatic triglyceride synthesis and enhanced fatty acid oxidation.
A climbing vine from Asia dubbed the immortality herb, rich in gypenosides structurally similar to ginsenosides; used as a powerful adaptogen, antioxidant, and cardiovascular tonic.
Gynostemma pentaphyllum, a climbing vine native to Asia and traditionally known as the 'immortality herb,' is rich in gypenosides—saponins structurally analogous to ginsenosides—and is used as an adaptogen for stress reduction, a cardiometabolic tonic for cholesterol and triglyceride management, and an antioxidant for anti-aging support. Its bioactive compounds include gypenosides, flavonoids, and polysaccharides, which contribute to its broad therapeutic profile. Evidence is limited to pilot studies and traditional use, placing it at evidence level C.
Gypenosides modulate the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol release and enhancing stress resilience. They also activate the Nrf2/ARE pathway, upregulating antioxidant enzymes such as superoxide dismutase and catalase, and improve endothelial function by increasing nitric oxide (NO) production via eNOS activation. Additionally, gypenosides influence lipid metabolism through PPARα agonism, leading to reduced hepatic triglyceride synthesis and enhanced fatty acid oxidation.