Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Peganum harmala var.
Persian traditional medicine uses harmal seeds as a fumigant against evil eye; active MAO inhibitors; also used in Moroccan and Central Asian traditions.
Harmal Persian (Peganum harmala var.) is a potent psychoactive plant used in traditional Persian, Moroccan, and Central Asian medicine for protection against the evil eye and as an anthelmintic. Its primary active compounds include the beta-carboline alkaloids harmine and harmaline, which are reversible MAO-A inhibitors, along with quinazoline alkaloids and vasicine. Modern research indicates potential antiparasitic, vasodilatory, and neuroactive properties, but its use is highly restricted due to serious safety risks including hypertensive crisis and serotonin syndrome.
The beta-carboline alkaloids harmine and harmaline act as reversible inhibitors of monoamine oxidase A (MAO-A), leading to increased levels of serotonin, norepinephrine, and dopamine in the brain. Additionally, these compounds interact with serotonin receptors (5-HT2A) and may modulate GABAergic and dopaminergic pathways. Vasicine exhibits bronchodilatory and uterine stimulant effects via histamine release and smooth muscle contraction. The quinazoline alkaloids contribute to the plant's overall pharmacological profile, including potential anti-inflammatory and antimicrobial actions.
Persian traditional medicine uses harmal seeds as a fumigant against evil eye; active MAO inhibitors; also used in Moroccan and Central Asian traditions.
Harmal Persian (Peganum harmala var.) is a potent psychoactive plant used in traditional Persian, Moroccan, and Central Asian medicine for protection against the evil eye and as an anthelmintic. Its primary active compounds include the beta-carboline alkaloids harmine and harmaline, which are reversible MAO-A inhibitors, along with quinazoline alkaloids and vasicine. Modern research indicates potential antiparasitic, vasodilatory, and neuroactive properties, but its use is highly restricted due to serious safety risks including hypertensive crisis and serotonin syndrome.
The beta-carboline alkaloids harmine and harmaline act as reversible inhibitors of monoamine oxidase A (MAO-A), leading to increased levels of serotonin, norepinephrine, and dopamine in the brain. Additionally, these compounds interact with serotonin receptors (5-HT2A) and may modulate GABAergic and dopaminergic pathways. Vasicine exhibits bronchodilatory and uterine stimulant effects via histamine release and smooth muscle contraction. The quinazoline alkaloids contribute to the plant's overall pharmacological profile, including potential anti-inflammatory and antimicrobial actions.