Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
An observational study reported parasite clearance in 76.6% of 120 patients in an earlier study; a subsequent study monitored pyrexia and parasitemia in 20 patients using a leaf paste [PMID:27914754]. In vivo tests in mice showed schizonticidal activity increased with doses of 100-200 mg/kg [PMID:35017935].
Hydroethanolic leaf extract (500 mg/kg BW) in rat models reduced paw volumes and inflammatory markers (TNF-α and COX-2) while increasing IL-10 [PMID:38116080]. In vitro studies showed downregulation of TNF-α [PMID:37630377].
Methanolic extract at 400 mg/kg in mice defended against the progress of pentylenetetrazol (PTZ)-induced kindling seizures and associated EEG changes [PMID:38776672].
Oral administration of a branched polysaccharide fraction (25 and 50 mg/kg) significantly inhibited citric acid-induced cough efforts in guinea pigs [PMID:25600986].
Alkaloid extracts from fruit and leaf showed cytotoxicity in HepG2 liver cancer cells, inducing apoptosis and reducing mitochondrial membrane potential [PMID:37162805, PMID:39711022].
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 23376280 (2013) — Nyctanthes arbor-tristis Linn--a critical ethnopharmacological review. · Journal of ethnopharmacology
- 2.PMID: 35017935 (2021) — Evaluation of In vivo Antimalarial Property of Nyctanthes arbor-tristis (Night Jasmine) Leaves. · Journal of pharmacy & bioallied sciences
- 3.PMID: 41213599 (2026) — Nyctanthes arbor-tristis: A Multifaceted Medicinal Plant in Traditional and Contemporary Medicine. · Planta medica
- 4.PMID: 38148217 (2023) — Genomic and Transcriptomic Analyses Illuminates Unique Traits of Elusive Night Flowering Jasmine Parijat (Nyctanthes arbor-tristis). · Physiologia plantarum
- 5.PMID: 39873741 (2026) — Nyctanthes arbor-tristis Linn.: comprehensive insights into its medicinal, phytochemical and safety profiles.