Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Hyoscyamus niger
Highly toxic European herb used cautiously in traditional medicine as an analgesic, antispasmodic, and sedative. Witches used it in flying ointments. Contains tropane alkaloids.
Henbane (Hyoscyamus niger) is a highly toxic Solanaceae herb containing tropane alkaloids (hyoscyamine, scopolamine, atropine) with potent anticholinergic properties. Historically used as an analgesic, antispasmodic, and sedative in folk medicine and witchcraft, its modern application is limited to pharmaceutical preparations due to a narrow therapeutic index. Key compounds are derived for clinical use in motion sickness, anesthesia adjuncts, and antispasmodic agents.
The tropane alkaloids competitively antagonize muscarinic acetylcholine receptors (M1–M5), blocking parasympathetic neurotransmission. This produces antispasmodic effects on smooth muscle, reduces secretions, and induces central sedation at low doses. At higher doses, central anticholinergic syndrome occurs, characterized by delirium, hallucinations, tachycardia, and respiratory depression. Scopolamine specifically exhibits greater central nervous system activity, making it useful for motion sickness and preanesthetic sedation.
Highly toxic European herb used cautiously in traditional medicine as an analgesic, antispasmodic, and sedative. Witches used it in flying ointments. Contains tropane alkaloids.
Henbane (Hyoscyamus niger) is a highly toxic Solanaceae herb containing tropane alkaloids (hyoscyamine, scopolamine, atropine) with potent anticholinergic properties. Historically used as an analgesic, antispasmodic, and sedative in folk medicine and witchcraft, its modern application is limited to pharmaceutical preparations due to a narrow therapeutic index. Key compounds are derived for clinical use in motion sickness, anesthesia adjuncts, and antispasmodic agents.
The tropane alkaloids competitively antagonize muscarinic acetylcholine receptors (M1–M5), blocking parasympathetic neurotransmission. This produces antispasmodic effects on smooth muscle, reduces secretions, and induces central sedation at low doses. At higher doses, central anticholinergic syndrome occurs, characterized by delirium, hallucinations, tachycardia, and respiratory depression. Scopolamine specifically exhibits greater central nervous system activity, making it useful for motion sickness and preanesthetic sedation.