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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Hypsizygus tessellatus
East Asian mushroom cultivated for food and immune support; eritadenine lowers cholesterol.
Hypsizygus tessellatus, commonly known as shimeji mushroom, is an East Asian culinary-medicinal fungus valued for immune modulation and cholesterol reduction. Its primary active compounds include eritadenine, which lowers serum cholesterol via inhibition of HMG-CoA reductase, and beta-glucans that stimulate innate immune responses. The mushroom is also a rich source of ergosterol and B vitamins, contributing to its nutritive and potential anti-tumor properties.
Eritadenine acts as a potent hypolipidemic agent by competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby reducing hepatic cholesterol production. Beta-glucans, particularly (1→3),(1→6)-β-D-glucans, activate dectin-1 receptors on macrophages and dendritic cells, enhancing phagocytosis and cytokine release (e.g., IL-6, TNF-α). Polysaccharides also modulate gut microbiota, promoting short-chain fatty acid production that supports immune homeostasis. Ergosterol, upon UV exposure, converts to vitamin D2, contributing to calcium metabolism and potential anti-proliferative effects.
East Asian mushroom cultivated for food and immune support; eritadenine lowers cholesterol.
Hypsizygus tessellatus, commonly known as shimeji mushroom, is an East Asian culinary-medicinal fungus valued for immune modulation and cholesterol reduction. Its primary active compounds include eritadenine, which lowers serum cholesterol via inhibition of HMG-CoA reductase, and beta-glucans that stimulate innate immune responses. The mushroom is also a rich source of ergosterol and B vitamins, contributing to its nutritive and potential anti-tumor properties.
Eritadenine acts as a potent hypolipidemic agent by competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby reducing hepatic cholesterol production. Beta-glucans, particularly (1→3),(1→6)-β-D-glucans, activate dectin-1 receptors on macrophages and dendritic cells, enhancing phagocytosis and cytokine release (e.g., IL-6, TNF-α). Polysaccharides also modulate gut microbiota, promoting short-chain fatty acid production that supports immune homeostasis. Ergosterol, upon UV exposure, converts to vitamin D2, contributing to calcium metabolism and potential anti-proliferative effects.