Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cephaelis ipecacuanha
An Amazonian herb used for centuries to treat dysentery and as an expectorant for respiratory conditions.
Ipecac root (Carapichea ipecacuanha) is a traditional Amazonian herb used primarily as an emetic and expectorant, with historical applications for dysentery and respiratory congestion. Its key active compounds, emetine and cephaeline, provide amoebicidal and expectorant effects, but also pose cardiotoxic risks at high doses. At low doses (15–30 mg alkaloid equivalent), it acts as an expectorant; at higher doses, it induces vomiting.
Emetine and cephaeline stimulate gastric mucosal irritant receptors, which activate the chemoreceptor trigger zone (CTZ) in the medulla oblongata, leading to emesis. These alkaloids also inhibit protein synthesis in protozoan cells, conferring amoebicidal activity. Additionally, they interfere with cardiac ion channels and mitochondrial function, causing dose-dependent cardiotoxicity.
An Amazonian herb used for centuries to treat dysentery and as an expectorant for respiratory conditions.
Ipecac root (Carapichea ipecacuanha) is a traditional Amazonian herb used primarily as an emetic and expectorant, with historical applications for dysentery and respiratory congestion. Its key active compounds, emetine and cephaeline, provide amoebicidal and expectorant effects, but also pose cardiotoxic risks at high doses. At low doses (15–30 mg alkaloid equivalent), it acts as an expectorant; at higher doses, it induces vomiting.
Emetine and cephaeline stimulate gastric mucosal irritant receptors, which activate the chemoreceptor trigger zone (CTZ) in the medulla oblongata, leading to emesis. These alkaloids also inhibit protein synthesis in protozoan cells, conferring amoebicidal activity. Additionally, they interfere with cardiac ion channels and mitochondrial function, causing dose-dependent cardiotoxicity.