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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cassia obtusifolia
Seeds used in TCM to clear liver heat, improve vision, moisten the intestines, and treat hypertension and constipation.
Jue Ming Zi (Cassia obtusifolia) is a traditional Chinese medicinal herb derived from the seeds, primarily used to clear liver heat, improve vision, and treat hypertension and constipation. Its key active compounds include anthraquinones (chrysophanol, emodin) and naphthopyrone glycosides, which contribute to its laxative, antihypertensive, and cholesterol-lowering effects. Evidence level C indicates limited clinical data supporting these uses.
The anthraquinones emodin and chrysophanol stimulate intestinal peristalsis and increase water secretion in the colon via activation of enteric neurons and inhibition of Na+/K+-ATPase, producing a laxative effect. Naphthopyrone glycosides and obtusin may lower blood pressure through vasodilation mediated by nitric oxide release and inhibition of angiotensin-converting enzyme (ACE). Additionally, these compounds reduce serum cholesterol by upregulating LDL receptor expression and inhibiting HMG-CoA reductase. The herb's hepatoprotective and anti-inflammatory actions are attributed to modulation of NF-κB and Nrf2 pathways.
Seeds used in TCM to clear liver heat, improve vision, moisten the intestines, and treat hypertension and constipation.
Jue Ming Zi (Cassia obtusifolia) is a traditional Chinese medicinal herb derived from the seeds, primarily used to clear liver heat, improve vision, and treat hypertension and constipation. Its key active compounds include anthraquinones (chrysophanol, emodin) and naphthopyrone glycosides, which contribute to its laxative, antihypertensive, and cholesterol-lowering effects. Evidence level C indicates limited clinical data supporting these uses.
The anthraquinones emodin and chrysophanol stimulate intestinal peristalsis and increase water secretion in the colon via activation of enteric neurons and inhibition of Na+/K+-ATPase, producing a laxative effect. Naphthopyrone glycosides and obtusin may lower blood pressure through vasodilation mediated by nitric oxide release and inhibition of angiotensin-converting enzyme (ACE). Additionally, these compounds reduce serum cholesterol by upregulating LDL receptor expression and inhibiting HMG-CoA reductase. The herb's hepatoprotective and anti-inflammatory actions are attributed to modulation of NF-κB and Nrf2 pathways.