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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Juniperus sabina
A toxic European juniper historically used as an abortifacient; extremely dangerous and not for therapeutic use.
Juniperus sabina is a highly toxic species of juniper historically employed as an abortifacient, anthelmintic, and topical treatment for skin conditions. Its primary active compounds include sabinol, thujone, podophyllotoxin, and various terpenes, which contribute to its severe hepatotoxicity, nephrotoxicity, and neurotoxicity. Due to its extreme danger, it has no safe therapeutic use and is only of historical toxicological interest.
Sabinol and thujone act as GABA-A receptor antagonists, leading to neuroexcitation and seizures, while podophyllotoxin inhibits microtubule assembly, causing mitotic arrest in rapidly dividing cells. The terpene fraction induces direct cellular damage through membrane disruption and oxidative stress. These combined actions result in profound gastrointestinal, hepatic, renal, and neurological toxicity, with the abortifacient effect stemming from uterine smooth muscle stimulation and fetal toxicity.
A toxic European juniper historically used as an abortifacient; extremely dangerous and not for therapeutic use.
Juniperus sabina is a highly toxic species of juniper historically employed as an abortifacient, anthelmintic, and topical treatment for skin conditions. Its primary active compounds include sabinol, thujone, podophyllotoxin, and various terpenes, which contribute to its severe hepatotoxicity, nephrotoxicity, and neurotoxicity. Due to its extreme danger, it has no safe therapeutic use and is only of historical toxicological interest.
Sabinol and thujone act as GABA-A receptor antagonists, leading to neuroexcitation and seizures, while podophyllotoxin inhibits microtubule assembly, causing mitotic arrest in rapidly dividing cells. The terpene fraction induces direct cellular damage through membrane disruption and oxidative stress. These combined actions result in profound gastrointestinal, hepatic, renal, and neurological toxicity, with the abortifacient effect stemming from uterine smooth muscle stimulation and fetal toxicity.