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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Cinnamomum + Poria + Peach formula
Classical Kampo and TCM formula for blood stasis in the lower abdomen — one of the most prescribed Kampo formulas for gynecological blood stasis.
Keishi-bukuryo-gan is a classical Kampo formula combining Cinnamomum, Poria, and Peach kernel, primarily indicated for gynecological blood stasis conditions such as dysmenorrhea, endometriosis, and uterine fibroids. Its key active compounds include cinnamaldehyde, paeoniflorin, and pachymic acid, which contribute to its antiplatelet, anti-inflammatory, and hormonal modulating effects. Despite widespread traditional use, clinical evidence remains limited (Level C), with most data derived from small trials and traditional experience.
The formula exerts its effects through multiple mechanisms: cinnamaldehyde inhibits platelet aggregation via suppression of thromboxane A2 and activation of nitric oxide pathways; paeoniflorin modulates the hypothalamic-pituitary-ovarian axis and reduces prostaglandin synthesis, thereby alleviating dysmenorrhea; pachymic acid exhibits anti-inflammatory activity by inhibiting NF-κB and COX-2 expression. Additionally, the combination may improve pelvic microcirculation and reduce endometrial hyperplasia through estrogen receptor modulation.
Classical Kampo and TCM formula for blood stasis in the lower abdomen — one of the most prescribed Kampo formulas for gynecological blood stasis.
Keishi-bukuryo-gan is a classical Kampo formula combining Cinnamomum, Poria, and Peach kernel, primarily indicated for gynecological blood stasis conditions such as dysmenorrhea, endometriosis, and uterine fibroids. Its key active compounds include cinnamaldehyde, paeoniflorin, and pachymic acid, which contribute to its antiplatelet, anti-inflammatory, and hormonal modulating effects. Despite widespread traditional use, clinical evidence remains limited (Level C), with most data derived from small trials and traditional experience.
The formula exerts its effects through multiple mechanisms: cinnamaldehyde inhibits platelet aggregation via suppression of thromboxane A2 and activation of nitric oxide pathways; paeoniflorin modulates the hypothalamic-pituitary-ovarian axis and reduces prostaglandin synthesis, thereby alleviating dysmenorrhea; pachymic acid exhibits anti-inflammatory activity by inhibiting NF-κB and COX-2 expression. Additionally, the combination may improve pelvic microcirculation and reduce endometrial hyperplasia through estrogen receptor modulation.