Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
A double-blinded clinical study demonstrated that A. gigas Nakai root extract (ARE) lotion significantly improved anti-wrinkle properties and increased type I collagen production by 40% in vitro [PMID:35460310]
The multi-herbal formula SH003 (containing A. gigas) has shown potential as a chemotherapeutic agent in in vitro and in vivo studies, with a clinical trial performed to identify the maximum tolerated dose in solid cancer patients [PMID:35205836, PMID:40295067]
Methanol extracts of A. gigas root significantly reduced infarction volumes and morphological deterioration in mouse models of stroke [PMID:32983252, PMID:34062098]
A. gigas extract restored diminished vascular relaxation responses to acetylcholine in high fat diet rats [PMID:38095615]
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 39128302 (2024) — The multi-herbal decoction SH003 alleviates LPS-induced acute lung injury by targeting inflammasome and extracellular traps in neutrophils. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 39779619 (2025) — Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy - active Phytochemicals and In Vivo Molecular Targets. · Pharmaceutical research
- 3.PMID: 29215592 (2017) — Natural Korean Medicine Dang-Gui: Biosynthesis, Effective Extraction and Formulations of Major Active Pyranocoumarins, Their Molecular Action Mechanism in Cancer, and Other Biological Activities. · Molecules (Basel, Switzerland)
- 4.PMID: 28452965 (2017) — Neuroprotective and Cognitive Enhancement Potentials of Angelica gigas Nakai Root: A Review. · Scientia pharmaceutica
- 5.PMID: 30652050