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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Neopicrorhiza scrophulariiflora
Tibetan medicine herb for liver and digestive conditions.
Kutki Tibetan (Neopicrorhiza scrophulariiflora) is a bitter herb used in Tibetan medicine primarily for hepatoprotective, cholagogue, and immune-modulating effects. Its key active compounds include picroside I, picroside II, kutkoside, and androsin, which contribute to its therapeutic actions on the liver and digestive system.
The hepatoprotective mechanism involves upregulation of antioxidant enzymes (e.g., superoxide dismutase, glutathione peroxidase) and inhibition of pro-inflammatory cytokines (e.g., TNF-α, IL-6) via NF-κB pathway modulation. Picrosides stimulate bile secretion by acting on cholangiocytes and enhance phase II detoxification enzymes. Androsin exhibits immunomodulatory effects by modulating T-cell responses and macrophage activity. The bitter principles also stimulate gastric and pancreatic secretions via bitter taste receptors (TAS2Rs) in the gut.
Tibetan medicine herb for liver and digestive conditions.
Kutki Tibetan (Neopicrorhiza scrophulariiflora) is a bitter herb used in Tibetan medicine primarily for hepatoprotective, cholagogue, and immune-modulating effects. Its key active compounds include picroside I, picroside II, kutkoside, and androsin, which contribute to its therapeutic actions on the liver and digestive system.
The hepatoprotective mechanism involves upregulation of antioxidant enzymes (e.g., superoxide dismutase, glutathione peroxidase) and inhibition of pro-inflammatory cytokines (e.g., TNF-α, IL-6) via NF-κB pathway modulation. Picrosides stimulate bile secretion by acting on cholangiocytes and enhance phase II detoxification enzymes. Androsin exhibits immunomodulatory effects by modulating T-cell responses and macrophage activity. The bitter principles also stimulate gastric and pancreatic secretions via bitter taste receptors (TAS2Rs) in the gut.