Lamium Album Herb (Lamium album): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Lamium album work as a medicinal herb?

Lamium album exerts its medicinal effects primarily through its astringent tannins and anti-inflammatory iridoids, including lamioside. The tannins bind to proteins in mucous membranes, creating a protective layer that reduces secretions and tightens tissues—explaining its traditional use for vaginal discharge and wound healing. The flavonoids contribute additional anti-inflammatory and antioxidant activity. Evidence level: C (preclinical and traditional use data).

Does white dead-nettle interact with any medications?

There are no well-documented drug interactions for Lamium album in the scientific literature. However, the herb contains tannins, which can theoretically reduce the absorption of certain medications, particularly alkaloids and iron supplements. As a precaution, separate administration by 2-3 hours when taking oral medications. Evidence level: C (theoretical based on constituent profile). Always consult a healthcare provider before combining herbs with prescription medications.

What is the recommended dosage for Lamium album?

The standard adult dosage for Lamium album is 3-6 grams of dried herb daily, prepared as a tea or taken as a tincture. For tea, steep 3-6g of dried aerial parts in 250ml of hot water for 10-15 minutes, consumed up to three times daily. For tincture preparations, follow manufacturer instructions or consult a qualified herbalist. Evidence level: C (traditional use guidelines).

Is Lamium album safe to take during pregnancy?

Lamium album is contraindicated during pregnancy. At therapeutic doses, the herb demonstrates emmenagogue properties, meaning it can stimulate uterine contractions and potentially induce menstruation or threaten pregnancy. Traditional use data and constituent analysis support this caution. Pregnant women should avoid all preparations of white dead-nettle. Evidence level: C (traditional use and pharmacological plausibility). Consult a qualified healthcare provider for pregnancy-safe alternatives.

Can white dead-nettle help with vaginal discharge?

Lamium album has a long history in European folk medicine for managing leucorrhea (excessive vaginal discharge). Its high tannin content provides astringent effects that help reduce excessive secretions and soothe inflamed mucous membranes. The herb is typically used as a tea for internal use or as an external wash. Evidence level: C (traditional use with supporting pharmacological data). Women experiencing persistent vaginal discharge should consult a healthcare provider to rule out infection.

Is Lamium album effective for wound healing?

Yes, Lamium album has been traditionally used for wound healing due to its combination of astringent tannins and anti-inflammatory compounds. The tannins help tighten tissues and reduce minor bleeding, while iridoids and flavonoids support the inflammatory response and tissue repair. It can be applied topically as a poultice or wash, or taken internally to support healing. Evidence level: C (traditional use with supporting pharmacological data).

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Lamium album (white dead-nettle) is a medicinal flowering plant used in traditional medicine for its anti-inflammatory, antioxidant, and antimicrobial properties [PMID: 41785535, 26019631].

Contexte

Lamium album is a perennial wildflower widely distributed across continents, including Eurasia [PMID: 40192867, 37156083]. It belongs to the Lamiaceae family and is closely related to other Lamium species such as L. barbatum [PMID: 41230035].

Usages traditionnels

Traditional applications include the use of aerial parts and roots in human and veterinary medicine [PMID: 31259737]. It is used to provide relief from pain in rheumatism, vaginal and cervical inflammation [PMID: 30366450], and is recommended for upper respiratory tract disorders or as a topical medication for mild inflammation of the throat, mouth, and skin [PMID: 32283643]. It is also assigned antiseptic, mucolytic, and antispasmodic activities for conditions like chronic bronchitis and pharyngitis [PMID: 28371943, 26019631].

Composés actifs

The plant contains iridoids (including lamalbid, shanzhiside methyl ester, and lamiridosins A and B) [PMID: 32283643, 19904996, 30366450], phenylpropanoids (verbascoside, phlinoside D, and acteoside) [PMID: 30366450, 7766391], flavonoids (rutin, quercetin, and tiliroside) [PMID: 32283643, 7766391], and phenolic acids (caffeic, chlorogenic, ferulic, gallic, p-coumaric, protocatechuic, syringic, gentisic, and vanillic acids) [PMID: 33352709]. It also contains sapogenins such as hederagenin and oleanolic acid [PMID: 34946786], as well as magnesium, potassium, and phosphorus [PMID: 40192867].

Mécanisme d'action

Lamium album extracts have demonstrated the ability to reduce KCl-induced tracheal smooth muscle contraction [PMID: 30151306]. In human neutrophils, certain compounds inhibit the secretion of inflammatory cytokines such as IL-8 and TNF-α [PMID: 30366450]. Additionally, it has shown the ability to scavenge reactive oxygen species (ROS) and decrease nitric oxide (NO) production in human corneal epithelial cells [PMID: 26730306].

Preuves cliniques

Preuve BAtopic dermatitis

A tri-herbal combination including Lamium album showed no significant advantage over placebo in objective or subjective parameters [PMID: 15793525]

Preuve BOsteoarthritic pain (base-of-thumb)

Lamium album leaf was used as a placebo and showed significantly less reduction in pain and disability compared to Urtica dioica sting [PMID: 10911825]

Preuve DHaemostasis

Butanolic extracts of L. album demonstrated haemostatic activity in rat models, comparable to vitamin K [PMID: 31259737]

Preuve DTracheal contraction

Hydroalcoholic extract (5 mg/ml) significantly reduced KCl-induced tracheal contraction in rats [PMID: 30151306]

Preuve DDiabetes

Hydroalcoholic extract (100 mg/kg) in diabetic rats reduced GSK-3 beta levels [PMID: 31970022]

Sécurité et effets indésirables

Acute toxicity tests of butanolic extracts in Wistar rats showed no toxicity [PMID: 31259737]. In vitro tests on human corneal epithelial cells showed that extracts did not affect cell viability at concentrations up to 125 μg/ml [PMID: 26730306].

Synthèse des preuves

The evidence consists primarily of in vitro studies and animal models (Level D), with limited clinical trials (Level B) where the herb served as a placebo or part of a combination that showed no superiority over placebo. There is strong phytochemical characterization of its bioactive compounds.

Sources PubMed

1.PMID: 31259737 (2019) — Haemostatic activity of butanolic extracts of Lamium album and Lamium purpureum aerial parts. · Acta pharmaceutica (Zagreb, Croatia)
2.PMID: 37999514 (2023) — Lamium album Flower Extracts: A Novel Approach for Controlling Fusarium Growth and Mycotoxin Biosynthesis. · Toxins
3.PMID: 40192867 (2025) — Application of Lamium album Leaves Powder in Wheat Bread Technology. · Plant foods for human nutrition (Dordrecht, Netherlands)
4.PMID: 33352709 (2020) — Phenolic Constituents of Lamium album L. subsp. album Flowers: Anatomical, Histochemical, and Phytochemical Study. · Molecules (Basel, Switzerland)
5.PMID: 41230035 (2025) — Complete chloroplast genomes analysis of Lamium barbatum and Leucas ciliata (Lamiaceae). · Mitochondrial DNA. Part B, Resources

Lamium Album Herb

Sources et citations

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