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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Consolida ajacis
Annual garden flower with delphinium-like appearance; seeds toxic but aerial parts used in folk medicine topically for lice and parasites.
Larkspur (Consolida ajacis) is an annual garden plant whose aerial parts have been used traditionally as a topical treatment for lice and parasites. Its primary active compounds include toxic diterpenoid alkaloids such as delsoline, ajacine, and consolinine, which confer insecticidal properties but also pose significant risk of poisoning if ingested. Evidence for its efficacy is limited to traditional use and preliminary pharmacological studies.
The diterpenoid alkaloids in Larkspur (e.g., ajacine, delsoline) act as neuromuscular blocking agents by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction, leading to flaccid paralysis in insects. In mammals, these compounds can inhibit sodium channel inactivation, causing cardiac arrhythmias and respiratory depression. Flavonoids present may contribute mild anti-inflammatory effects, but the primary mechanism is neurotoxic.
Annual garden flower with delphinium-like appearance; seeds toxic but aerial parts used in folk medicine topically for lice and parasites.
Larkspur (Consolida ajacis) is an annual garden plant whose aerial parts have been used traditionally as a topical treatment for lice and parasites. Its primary active compounds include toxic diterpenoid alkaloids such as delsoline, ajacine, and consolinine, which confer insecticidal properties but also pose significant risk of poisoning if ingested. Evidence for its efficacy is limited to traditional use and preliminary pharmacological studies.
The diterpenoid alkaloids in Larkspur (e.g., ajacine, delsoline) act as neuromuscular blocking agents by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction, leading to flaccid paralysis in insects. In mammals, these compounds can inhibit sodium channel inactivation, causing cardiac arrhythmias and respiratory depression. Flavonoids present may contribute mild anti-inflammatory effects, but the primary mechanism is neurotoxic.