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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Lentinus edodes
East Asian culinary mushroom; lentinan polysaccharide approved in Japan as cancer immunotherapy adjunct.
Lentinus edodes (shiitake) is an East Asian culinary mushroom with documented immunomodulatory, antitumor, and cardiovascular benefits. Its key active compounds include lentinan (a beta-glucan approved in Japan as an adjunct for cancer therapy), eritadenine (a cholesterol-lowering agent), and other beta-glucans. Evidence supports its use as an immunostimulant, though most studies are limited to preclinical or small clinical trials.
Lentinan and other beta-glucans activate innate immune cells (macrophages, NK cells, dendritic cells) via dectin-1 and TLR2/4 receptors, enhancing cytokine production (IL-12, IFN-γ) and cytotoxic T-cell activity. Eritadenine reduces serum cholesterol by inhibiting hepatic HMG-CoA reductase and increasing LDL receptor expression. Additionally, eritadenine may modulate platelet aggregation via adenosine receptor pathways.
East Asian culinary mushroom; lentinan polysaccharide approved in Japan as cancer immunotherapy adjunct.
Lentinus edodes (shiitake) is an East Asian culinary mushroom with documented immunomodulatory, antitumor, and cardiovascular benefits. Its key active compounds include lentinan (a beta-glucan approved in Japan as an adjunct for cancer therapy), eritadenine (a cholesterol-lowering agent), and other beta-glucans. Evidence supports its use as an immunostimulant, though most studies are limited to preclinical or small clinical trials.
Lentinan and other beta-glucans activate innate immune cells (macrophages, NK cells, dendritic cells) via dectin-1 and TLR2/4 receptors, enhancing cytokine production (IL-12, IFN-γ) and cytotoxic T-cell activity. Eritadenine reduces serum cholesterol by inhibiting hepatic HMG-CoA reductase and increasing LDL receptor expression. Additionally, eritadenine may modulate platelet aggregation via adenosine receptor pathways.